[HTML][HTML] Body mass index may predict the response to ipilimumab in metastatic melanoma: An observational multi-centre study

G Richtig, C Hoeller, M Wolf, I Wolf, BM Rainer… - PLoS …, 2018 - journals.plos.org
Introduction Immunotherapy is a well-established treatment option in patients with metastatic
melanoma. However, biomarkers that can be used to predict a response in these patients …

[HTML][HTML] Real-life use of talimogene laherparepvec (T-VEC) in melanoma patients in centers in Austria, Switzerland and Germany

JM Ressler, M Karasek, L Koch… - … for ImmunoTherapy of …, 2021 - ncbi.nlm.nih.gov
Background Talimogene laherparepvec (T-VEC) is a licensed therapy for use in melanoma
patients of stage IIIB-IVM1a with injectable, unresectable metastatic lesions in Europe …

[HTML][HTML] Ocular toxicity due to trametinib and dabrafenib

S Sarny, M Neumayer, J Kofler, Y El-Shabrawi - BMC ophthalmology, 2017 - Springer
Background To report a case of uveitis and neuroretinal detachment in a patient treated with
Trametinib and Dabrafenib due to metastatic cutaneous melanoma stage IV. Case …

[HTML][HTML] Toward systematic understanding of flower bud induction in apple: a multi-omics approach

A Milyaev, J Kofler, I Klaiber, S Czemmel… - Frontiers in Plant …, 2021 - frontiersin.org
The induction of flower buds in apple (Malus× domestica Borkh.) is tightly connected to
biennial bearing, which is characterized by alternating years with high (ON) and low or no …

[HTML][HTML] A new approach for analyzing and interpreting data on fruit drop in mango

MH Hagemann, MG Roemer, J Kofler, M Hegele… - …, 2014 - journals.ashs.org
Mango yields are frequently reduced by premature fruit drop, induced by plant stresses
during the fruit set period in response to unsuitable climatic or crop management conditions …

[HTML][HTML] Proteomic differences in apple spur buds from high and non-cropping trees during floral initiation

J Kofler, A Milyaev, B Würtz, J Pfannstiel… - Journal of …, 2022 - Elsevier
The cropping behavior of biennial apple (Malus× domestica Borkh.) cultivars is irregular and
often follows a biennial bearing pattern with 'On'years (high crop load and inhibited floral …

[HTML][HTML] High crop load and low temperature delay the onset of bud initiation in apple

J Kofler, A Milyaev, F Capezzone, S Stojnić, N Mićić… - Scientific Reports, 2019 - nature.com
The reproductive cycle of apple (Malus× domestica Borkh.) starts with the induction of floral
development, however, first morphological changes within the bud appear during the …

Normalized chlorophyll fluorescence imaging: A method to determine irradiance and photosynthetically active radiation in phytoplankton cultures

A Zavafer, H Bates, L Labeeuw, JR Kofler, PJ Ralph - Algal Research, 2021 - Elsevier
In order to expand microalgae's use as a mainstream biotechnological resource, the
efficiency of light capturing in culture vessels must be optimised. As a response to the …

Profiling of phytohormones in apple fruit and buds regarding their role as potential regulators of flower bud formation

A Milyaev, J Kofler, YAT Moya, J Lempe… - Tree …, 2022 - academic.oup.com
Abstract Apple (Malus× domestica Borkh.) cropping behavior, if not regulated, is often
manifested by high yields of small-sized fruit in so called ON-years, which are usually …

[HTML][HTML] Dabrafenib plus trametinib in unselected advanced BRAF V600–mut melanoma: a non-interventional, multicenter, prospective trial

E Richtig, VA Nguyen, P Koelblinger, I Wolf… - Melanoma …, 2024 - journals.lww.com
Objective The efficacy of combined BRAF and MEK inhibition for BRAF V600–mutant
melanoma in a broad patient population, including subgroups excluded from phase 3 trials …