Comparative study of liposomes, transfersomes, ethosomes and cubosomes for transcutaneous immunisation: characterisation and in vitro skin penetration

T Rattanapak, K Young, T Rades… - Journal of Pharmacy and …, 2012 - academic.oup.com
Objectives Lipid colloidal vaccines, including liposomes, transfersomes, ethosomes and
cubosomes, were formulated, characterised and investigated for their ability to enhance …

Cubosomes containing the adjuvants imiquimod and monophosphoryl lipid A stimulate robust cellular and humoral immune responses

SB Rizwan, WT McBurney, K Young, T Hanley… - Journal of controlled …, 2013 - Elsevier
New generation vaccines increasingly utilize highly purified peptides and proteins as the
target antigen, however these are often poorly immunogenic. One of the most promising …

Landscape predictors of stream dissolved organic matter concentration and physicochemistry in a Lake Superior river watershed

PC Frost, JH Larson, CA Johnston, KC Young… - Aquatic Sciences, 2006 - Springer
We examined landscape predictors of dissolved organic matter (DOM) concentration,
molecular weight (M w), and molar absorptivity at 280 nm (ɛ 280) in 60 streams from the …

Fertility counseling before cancer treatment and subsequent reproductive concerns among female adolescent and young adult cancer survivors

K Young, K Shliakhtsitsava, L Natarajan, E Myers… - Cancer, 2019 - Wiley Online Library
Background Fertility counseling before cancer treatment has been advocated by clinical
guidelines, though little is known about its long‐term impact on the unique reproductive …

[HTML][HTML] Plastic surgery training in the UK: results from a national survey of trainee experiences

M Fell, R Staruch, BG Baker, R Nicholas, R Howes… - JPRAS open, 2020 - Elsevier
Background Plastic surgery training in the UK continues to evolve towards an outcome-
based rather than time-served curriculum. UK plastic surgery trainees are appointed …

Levonorgestrel intrauterine system for endometrial protection in women with breast cancer on adjuvant tamoxifen

SAD Romero, K Young, M Hickey… - Cochrane Database of …, 2020 - cochranelibrary.com
Background Adjuvant tamoxifen reduces the risk of breast cancer recurrence in women with
oestrogen receptor‐positive breast cancer. Tamoxifen also increases the risk of …

The effect of trainee research collaboratives in the UK

D Nepogodiev, SJ Chapman, AG Kolias… - The Lancet …, 2017 - thelancet.com
Trainee-led networks have pioneered a novel collaborative approach to research in the UK.
1 Established at a similar time to the UK National Institute for Health Research in 2006 …

Controls on mixing‐dependent denitrification in hyporheic zones induced by riverbed dunes: A steady state modeling study

ET Hester, KI Young… - Water Resources …, 2014 - Wiley Online Library
The hyporheic zone is known to attenuate contaminants originating from surface water, yet
the ability of the hyporheic zone to attenuate contaminants in upwelling groundwater plumes …

Fracture-related infection

S Baertl, WJ Metsemakers, M Morgenstern… - Bone & Joint …, 2021 - boneandjoint.org.uk
Background Fracture-related infection (FRI) carries a substantial burden of disease and
socio-economic costs. 1-3 The incidence of FRI is 1% to 2% in closed fractures and can …

[HTML][HTML] Activated CD90/Thy-1 fibroblasts co-express the Δ133p53β isoform and are associated with highly inflamed rheumatoid arthritis

AK Wiles, S Mehta, M Millier, AG Woolley, K Li… - Arthritis Research & …, 2023 - Springer
Background The p53 isoform Δ133p53β is known to be associated with cancers driven by
inflammation. Many of the features associated with the development of inflammation in …