Phase II study of daily sunitinib in FDG-PET–positive, iodine-refractory differentiated thyroid cancer and metastatic medullary carcinoma of the thyroid with functional …
LL Carr, DA Mankoff, BH Goulart, KD Eaton… - Clinical Cancer …, 2010 - AACR
Purpose: We conducted a phase II study to assess the efficacy of continuous dosing of
sunitinib in patients with flurodeoxyglucose positron emission tomography (FDG-PET)–avid …
sunitinib in patients with flurodeoxyglucose positron emission tomography (FDG-PET)–avid …
[HTML][HTML] Plasma processing conditions substantially influence circulating microRNA biomarker levels
HH Cheng, HS Yi, Y Kim, EM Kroh, JW Chien… - PloS one, 2013 - journals.plos.org
Circulating, cell-free microRNAs (miRNAs) are promising candidate biomarkers, but optimal
conditions for processing blood specimens for miRNA measurement remain to be …
conditions for processing blood specimens for miRNA measurement remain to be …
[HTML][HTML] Validation and implementation of targeted capture and sequencing for the detection of actionable mutation, copy number variation, and gene rearrangement …
CC Pritchard, SJ Salipante, K Koehler, C Smith… - The Journal of Molecular …, 2014 - Elsevier
Recent years have seen development and implementation of anticancer therapies targeted
to particular gene mutations, but methods to assay clinical cancer specimens in a …
to particular gene mutations, but methods to assay clinical cancer specimens in a …
Cisplatin and radiotherapy with or without erlotinib in locally advanced squamous cell carcinoma of the head and neck: a randomized phase II trial
RG Martins, U Parvathaneni, JE Bauman… - Journal of clinical …, 2013 - ascopubs.org
Purpose The combination of cisplatin and radiotherapy is a standard treatment for patients
with locally advanced squamous cell carcinoma of the head and neck (SCCHN). Cetuximab …
with locally advanced squamous cell carcinoma of the head and neck (SCCHN). Cetuximab …
[HTML][HTML] Estrogen signaling in lung cancer: an opportunity for novel therapy
CS Baik, KD Eaton - Cancers, 2012 - mdpi.com
Lung cancer is the leading cause of cancer death in US and represents a major public
health burden. Epidemiologic data have suggested that lung cancer in women may possess …
health burden. Epidemiologic data have suggested that lung cancer in women may possess …
Targeting NOTCH activation in small cell lung cancer through LSD1 inhibition
A Augert, E Eastwood, AH Ibrahim, N Wu… - Science …, 2019 - science.org
Small cell lung cancer (SCLC) is a recalcitrant, aggressive neuroendocrine-type cancer for
which little change to first-line standard-of-care treatment has occurred within the last few …
which little change to first-line standard-of-care treatment has occurred within the last few …
Anti–PD-1 and anti–PDL-1 monoclonal antibodies causing type 1 diabetes
M Mellati, KD Eaton, BM Brooks-Worrell… - Diabetes …, 2015 - Am Diabetes Assoc
Checkpoint inhibitors have an anticancer effect by removing a negative regulatory signal for
T-cell activation from the tumor microenvironment (Fig. 1). They include cytotoxic T-cell …
T-cell activation from the tumor microenvironment (Fig. 1). They include cytotoxic T-cell …
Phase Ib trial of the toll-like receptor 8 agonist, motolimod (VTX-2337), combined with cetuximab in patients with recurrent or metastatic SCCHN
LQM Chow, C Morishima, KD Eaton, CS Baik… - Clinical cancer …, 2017 - AACR
Abstract Purpose: As Toll-like receptors (TLR) are key mediators of immune responses, TLR
agonists may be important for augmenting the efficacy of therapies for squamous cell …
agonists may be important for augmenting the efficacy of therapies for squamous cell …
Salvage lung resection after definitive radiation (> 59 Gy) for non-small cell lung cancer: surgical and oncologic outcomes
JE Bauman, MS Mulligan, RG Martins… - The Annals of thoracic …, 2008 - Elsevier
BACKGROUND: Isolated local relapse occurs in 24% to 35% of patients after definitive
chemoradiation for locally advanced non-small cell lung cancer. Although originally …
chemoradiation for locally advanced non-small cell lung cancer. Although originally …
Characterizing potentially preventable cancer-and chronic disease–related emergency department use in the year after treatment initiation: a regional study
L Panattoni, C Fedorenko… - Journal of oncology …, 2018 - ascopubs.org
Purpose: As new quality metrics and interventions for potentially preventable emergency
department (ED) visits are implemented, we sought to compare methods for evaluating the …
department (ED) visits are implemented, we sought to compare methods for evaluating the …