User profiles for "author:Kevin Tyan"

Kevin Tyan

Harvard Medical School
Verified email at hms.harvard.edu
Cited by 303

Cytokine changes during immune-related adverse events and corticosteroid treatment in melanoma patients receiving immune checkpoint inhibitors

K Tyan, J Baginska, M Brainard… - Cancer Immunology …, 2021 - Springer
Abstract Background Immune checkpoint inhibitors (ICIs) often cause immune-related
adverse events (irAEs), most of which are treated with corticosteroids despite evidence …

Vitamin D intake is associated with decreased risk of immune checkpoint inhibitor‐induced colitis

S Grover, M Dougan, K Tyan, A Giobbie‐Hurder… - Cancer, 2020 - Wiley Online Library
Background There is a lack of predictive markers informing on the risk of colitis in patients
treated with immune checkpoint inhibitors (ICIs). The aim of this study was to identify …

Oligometastatic adenoid cystic carcinoma: correlating tumor burden and time to treatment with outcomes

K Tyan, JE Bae, JH Lorch, DN Margalit… - Head & …, 2022 - Wiley Online Library
Background There is limited information on the management and outcomes of
oligometastases (OM) in adenoid cystic carcinoma (ACC). Methods Retrospective study of …

[HTML][HTML] Phase IB study of ziv-aflibercept plus pembrolizumab in patients with advanced solid tumors

OE Rahma, K Tyan, A Giobbie-Hurder… - … for Immunotherapy of …, 2022 - ncbi.nlm.nih.gov
Background The combination of antiangiogenic agents with immune checkpoint inhibitors
could potentially overcome immune suppression driven by tumor angiogenesis. We report …

Investing in our first line of defense: environmental services workers

K Tyan, PA Cohen - Annals of Internal Medicine, 2020 - acpjournals.org
Investing in Our First Line of Defense: Environmental Services Workers | Annals of Internal
Medicine Advertisement ACP Online Annals of Internal Medicine Annals of Internal Medicine …

Evaluation of the antimicrobial efficacy and skin safety of a novel color additive in combination with chlorine disinfectants

K Tyan, J Kang, K Jin, AM Kyle - American Journal of Infection Control, 2018 - Elsevier
Objective A novel color additive colorizes chlorine disinfectants blue to improve visibility and
enhance spray surface coverage, and it fades to colorless to indicate elapsed contact time …

Private equity acquisition of oncology clinics in the US from 2003 to 2022

K Tyan, MB Lam, M Milligan - JAMA Internal Medicine, 2023 - jamanetwork.com
Methods| In this cross-sectional study, using financial databases and publicly available data
(including press releases, news sources, clinic websites, and financial 10-K reports), we …

[HTML][HTML] A multiphase intervention of novel color additive for bleach disinfectant wipes improves thoroughness of cleaning in an academic medical center

K Tyan, JM Zuckerman, C Cutler, K Modupe… - American Journal of …, 2022 - Elsevier
Surface disinfection is critical for preventing healthcare-associated infections; however,
sustaining high-quality cleaning technique is challenging without constant feedback and …

FcγRIIB prevents inflammatory type I IFN production from plasmacytoid dendritic cells during a viral memory response

M Flores, C Chew, K Tyan, WQ Huang… - The Journal of …, 2015 - journals.aai.org
Abstract The type I IFN (IFN-α) response is crucial for viral clearance during primary viral
infections. Plasmacytoid dendritic cells (pDCs) are important early responders during …

Impact of COVID-19 on patients with Cancer receiving Immune Checkpoint inhibitors

ATN Bui, K Tyan, A Giobbie-Hurder… - Journal of …, 2021 - meridian.allenpress.com
Introduction To evaluate the impact of Sars-Cov-2 infection on mortality and immune
checkpoint inhibitor (ICI) toxicity in patients with cancer receiving ICIs compared to those not …