Abstract Background Sophora flavescens Aiton (SF), also known as Kushen (Chinese: 苦参),
has been an important species in Chinese medicine since the Qin and Han dynasties. It is …

The cure rate of osteosarcoma has not improved in the past 30 years. The search for new
treatments and drugs is urgently needed. Apatinib is a high selectivity inhibitor of vascular …

Background Immune checkpoint inhibitors have led to a breakthrough in solid tumor
immunotherapy, but related studies on musculoskeletal tumors are few, especially for PD …

Background Results of our previous study showed high objective response but short-term
activity of apatinib in advanced osteosarcoma. We aimed to investigate the activity of …

Current practices for the therapy of chondrosarcoma, including wide-margin surgical
resection and chemotherapy, are less than satisfactory. Recently, emerging evidence has …

Background Lung adenocarcinomas (LUADs) that display radiologically as subsolid
nodules (SSNs) exhibit more indolent biological behaviour than solid LUADs. SSNs …

Due to the prevalence of low-dose computed tomography (LDCT) screening, the detection
rate of lung cancer presenting as multiple groundglass opacities (GGOs) is increasing. In …

Background Expression of COP9 signalosome subunit 3 (COPS3), an oncogene
overexpressed in osteosarcoma, has been demonstrated to be significantly correlated with …

Background Multiple primary tumors, especially quadruple primary neoplasms is extremely
rare. Fibrous dysplasia (FD), osteosarcoma (OS), and giant cell tumor of bone (GCTB) are …

Introduction. Mucormycosis is a rare, invasive disease caused by opportunistic pathogens
related to the Mucorales order with high fatality rates in immunocompromised hosts …