Targeting the PD1/PD-L1 axis in melanoma: biological rationale, clinical challenges and opportunities
A dynamic interplay exists between host and tumor, and the ability of the tumor to evade
immune recognition often determines the clinical course of the disease. Significant …
immune recognition often determines the clinical course of the disease. Significant …
Axillary dissection versus no axillary dissection in patients with breast cancer and sentinel-node micrometastases (IBCSG 23-01): 10-year follow-up of a randomised …
Background We previously reported the 5-year results of the phase 3 IBCSG 23-01 trial
comparing disease-free survival in patients with breast cancer with one or more …
comparing disease-free survival in patients with breast cancer with one or more …
Genome-wide association meta-analyses combining multiple risk phenotypes provide insights into the genetic architecture of cutaneous melanoma susceptibility
Most genetic susceptibility to cutaneous melanoma remains to be discovered. Meta-analysis
genome-wide association study (GWAS) of 36,760 cases of melanoma (67% newly …
genome-wide association study (GWAS) of 36,760 cases of melanoma (67% newly …
Orientation-dependent stereo Wigner time delay and electron localization in a small molecule
J Vos, L Cattaneo, S Patchkovskii, T Zimmermann… - Science, 2018 - science.org
Attosecond metrology of atoms has accessed the time scale of the most fundamental
processes in quantum mechanics. Transferring the time-resolved photoelectric effect from …
processes in quantum mechanics. Transferring the time-resolved photoelectric effect from …
Colorectal adenocarcinomas harboring ALK fusion genes: a clinicopathologic and molecular genetic study of 12 cases and review of the literature
This study determined the frequency and the clinicopathologic and genetic features of
colorectal carcinomas driven by oncogenic fusions of the anaplastic lymphoma kinase gene …
colorectal carcinomas driven by oncogenic fusions of the anaplastic lymphoma kinase gene …
[HTML][HTML] Field-synchronized Digital Twin framework for production scheduling with uncertainty
Research on scheduling problems is an evergreen challenge for industrial engineers. The
growth of digital technologies opens the possibility to collect and analyze great amount of …
growth of digital technologies opens the possibility to collect and analyze great amount of …
Attosecond coupled electron and nuclear dynamics in dissociative ionization of H2
The interaction of an extreme-ultraviolet attosecond pulse with a molecular system suddenly
removes electrons, which can lead to significant changes in the chemical bonding and …
removes electrons, which can lead to significant changes in the chemical bonding and …
A computational model of drug delivery through microcirculation to compare different tumor treatments
L Cattaneo, P Zunino - International journal for numerical …, 2014 - Wiley Online Library
Starting from the fundamental laws of filtration and transport in biological tissues, we
develop a computational model to capture the interplay between blood perfusion, fluid …
develop a computational model to capture the interplay between blood perfusion, fluid …
Time delays from one-photon transitions in the continuum
Attosecond photoionization time delays reveal information about the potential energy
landscape that an outgoing electron wavepacket probes upon ionization. In this study, we …
landscape that an outgoing electron wavepacket probes upon ionization. In this study, we …
Comparison of attosecond streaking and RABBITT
Recent progress in the generation of ultra-short laser pulses has enabled the measurement
of photoionization time delays with attosecond precision. For single photoemission time …
of photoionization time delays with attosecond precision. For single photoemission time …