[HTML][HTML] p38 MAPK signaling in M1 macrophages results in selective elimination of M2 macrophages by MEK inhibition

D Baumann, J Drebant, T Hägele, L Burger… - … for Immunotherapy of …, 2021 - ncbi.nlm.nih.gov
M2 macrophages promote tumor progression and therapy resistance, whereas
proimmunogenic M1 macrophages can contribute to the efficacy of cytostatic and …

[HTML][HTML] Phosphate-dependent aggregation of [KL]n peptides affects their membranolytic activity

E Strandberg, F Schweigardt, P Wadhwani, J Bürck… - Scientific reports, 2020 - nature.com
In this study, we investigate how the length of amphiphilic β-sheet forming peptides affects
their interaction with membranes. Four polycationic model peptides with lengths from 6 to 18 …

[HTML][HTML] Membranolytic Mechanism of Amphiphilic Antimicrobial β-Stranded [KL]n Peptides

F Schweigardt, E Strandberg, P Wadhwani, J Reichert… - Biomedicines, 2022 - mdpi.com
Amphipathic peptides can act as antibiotics due to membrane permeabilization. KL peptides
with the repetitive sequence [Lys-Leu] n-NH2 form amphipathic β-strands in the presence of …

Retrospektive Analyse zur notwendigen Dauer der medikamentösen VTE-Prophylaxe bei Patientinnen mit primärer Mammakarzinom-Operation

AL Burger - 2022 - publikationen.sulb.uni-saarland.de
Venöse Thromboembolien stellen ein häufig vorkommendes Krankheitsbild dar und treten
insbesondere bei KrebspatientInnen vermehrt auf. Dabei nehmen Brustkrebspatientinnen …