[HTML][HTML] Tumor and immune remodeling following radiotherapy in human renal cell carcinoma

J Chow, A Khan, M Gaudieri, BJ Wasik… - … for Immunotherapy of …, 2023 - ncbi.nlm.nih.gov
Background Studies evaluating peripheral patient samples show radiation can modulate
immune responses, yet the biological changes in human tumors particularly at the cellular …

Abstract PO-038: Hide and Seq: radiation-induced immunogenicity of patient tumors revealed by single cell analysis

JL Chow, N Hoffend, M Gaudieri, S Abrams… - Clinical Cancer …, 2021 - AACR
Robust preclinical investigations into radiation-induced immunogenicity has led to increased
enthusiasm for combining radiation with immunotherapy. Promising results in a limited …

Seq-ing the source of radiation-induced anti-tumor immunogenicity in patient tumors

JL Chow, N Hoffend, M Gaudieri, SI Abrams… - The Journal of …, 2021 - journals.aai.org
Translational studies in a small number of patients have demonstrated a clinical benefit
when combining radiation and immunotherapy. These findings are supported by correlative …