CD5 and CD6 are closely related signal-transducing class I scavenger receptors mainly
expressed on lymphocytes. Both receptors are involved in the modulation of the activation …

Adoptive cell transfer (ACT) therapies have gained renewed interest in the field of
immunotherapy following the advent of chimeric antigen receptor (CAR) technology. This …

Introduction Antimicrobial resistance is a pressing global concern that has led to the search
for new antibacterial agents with novel targets or non-traditional approaches. Recently …

The worldwide emergence and spread of infections caused by multidrug-resistant bacteria
endangers the efficacy of current antibiotics in the clinical setting. The lack of new antibiotics …

Pathogens are one of the main selective pressures that ancestral humans had to adapt to.
Components of the immune response system have been preferential targets of natural …

Background and Aims Bacterial infections are common and severe in cirrhosis, but their
pathogenesis is poorly understood. Dysfunction of liver macrophages may play a role, but …

Crohn's disease (CD) and ulcerative colitis (UC) are inflammatory bowel diseases (IBD)
resulting from the interaction of multiple environmental, genetic and immunological factors …

Cancer management still requires more potent and safer treatments, of which
immunomodulatory receptors on the lymphocyte surface have started to show promise in …

Background Natural killer (NK) cells are important anti-tumor cells of our innate immune
system. Their anti-cancer activity is mediated through interaction of a wide array of activating …

Encapsulation of water-soluble bioactive compounds for enabling specific accumulation in
tumor locations, while avoiding premature clearance and/or degradation in the bloodstream …