The MICA-NKG2D axis in clear cell renal cell carcinoma bolsters MICA as target in immuno-oncology
F Secchiari, SY Nuñez, JM Sierra, A Ziblat… - …, 2022 - Taylor & Francis
ABSTRACT NKG2D is a major natural killer (NK) cell-activating receptor that recognizes
eight ligands (NKG2DLs), including MICA, and whose engagement triggers NK cell effector …
eight ligands (NKG2DLs), including MICA, and whose engagement triggers NK cell effector …
[HTML][HTML] Restoration of antitumor immunity through anti-MICA antibodies elicited with a chimeric protein
N Torres, MV Regge, F Secchiari… - … for Immunotherapy of …, 2020 - ncbi.nlm.nih.gov
Background Natural killer and cytotoxic CD8+ T cells are major players during antitumor
immunity. They express NKG2D, an activating receptor that promotes tumor elimination …
immunity. They express NKG2D, an activating receptor that promotes tumor elimination …
Tumor‐associated macrophages impair NK cell IFN‐γ production and contribute to tumor progression in clear cell renal cell carcinoma
SY Núñez, A Trotta, MV Regge… - European Journal of …, 2024 - Wiley Online Library
Tumor‐associated macrophages (TAM) are abundant in several tumor types and usually
correlate with poor prognosis. Previously, we demonstrated that anti‐inflammatory …
correlate with poor prognosis. Previously, we demonstrated that anti‐inflammatory …
Characterization of tumor infiltrating NK cells (TINK) and type 1 innate lymphoid cells (ILC1) in breast cancer
MC Santilli, MV Regge, M Gantov, AD Friedrich… - 2021 - ri.conicet.gov.ar
ILC1 and NK cells share several phenotypic and functional characteristics and display
plasticity because they can interconvert one into another in a context-dependent manner …
plasticity because they can interconvert one into another in a context-dependent manner …
Phenotype and functional alterations of human NK cells by organophosphate pesticides
AD Friedrich, JM Sierra, MV Regge, MC Santilli… - 2021 - notablesdelaciencia.conicet.gov.ar
Chlorpyrifos (CPF) and Glyphosate (GLY) are organophosphate pesticides widely used in
agriculture. Several evidences suggest that CPF-and GLY-based pesticides are genotoxic …
agriculture. Several evidences suggest that CPF-and GLY-based pesticides are genotoxic …
PD-L1 expression is induced on cytokine-stimulated human NK cells and contributes to IFN-γ production
JM Sierra, F Secchiari, SY Nuñez, MV Regge… - 2019 - datosdeinvestigacion.conicet.gov.ar
Natural Killer (NK) cells are critical effectors against tumor and virus-infected cells, and their
activity is modulated by multiple inhibitory and activating receptors and cytokines. Tumor …
activity is modulated by multiple inhibitory and activating receptors and cytokines. Tumor …
Creación de un Banco Provincial de Datos Genéticos. Análisis Bioético: alcances y limitaciones
W Bonillo, M del Huerto Revaz, LA Curti… - …, 2017 - eventosacademicos.filo.uba.ar
La bioética se comporta como un espacio interdisciplinario encargado de proponer un
conjunto de orientaciones instrumentales y normativas que guíen los procesos y decisiones …
conjunto de orientaciones instrumentales y normativas que guíen los procesos y decisiones …
[PDF][PDF] Determinación del efecto Bowditch en el modelo de estudio Drosophila melanogaster
MV Regge - 2017 - repositorio.unnoba.edu.ar
Drosophila melanogaster es un insecto holometábolo, perteneciente al orden Díptera ya la
familia Drosophilidae. De hábitat cosmopolita, consume alimentos con alto contenido de …
familia Drosophilidae. De hábitat cosmopolita, consume alimentos con alto contenido de …