[HTML][HTML] The role of stiffness in cell reprogramming: a potential role for biomaterials in inducing tissue regeneration
M d'Angelo, E Benedetti, MG Tupone, M Catanesi… - Cells, 2019 - mdpi.com
The mechanotransduction is the process by which cells sense mechanical stimuli such as
elasticity, viscosity, and nanotopography of extracellular matrix and translate them into …
elasticity, viscosity, and nanotopography of extracellular matrix and translate them into …
[HTML][HTML] MicroRNAs dysregulation and mitochondrial dysfunction in neurodegenerative diseases
M Catanesi, M d'Angelo, MG Tupone… - International Journal of …, 2020 - mdpi.com
Neurodegenerative diseases are debilitating and currently incurable conditions causing
severe cognitive and motor impairments, defined by the progressive deterioration of …
severe cognitive and motor impairments, defined by the progressive deterioration of …
[HTML][HTML] A state-of-the-art of functional scaffolds for 3D nervous tissue regeneration
MG Tupone, M d'Angelo, V Castelli… - … in Bioengineering and …, 2021 - frontiersin.org
Exploring and developing multifunctional intelligent biomaterials is crucial to improve next-
generation therapies in tissue engineering and regenerative medicine. Recent findings …
generation therapies in tissue engineering and regenerative medicine. Recent findings …
[HTML][HTML] BCL-XL overexpression promotes tumor progression-associated properties
D Trisciuoglio, MG Tupone, M Desideri… - Cell death & …, 2017 - nature.com
By using human melanoma and glioblastoma cell lines and their derivative BCL-XL
overexpressing clones, we investigated the role of BCL-XL in aggressive features of these …
overexpressing clones, we investigated the role of BCL-XL in aggressive features of these …
[HTML][HTML] Olive leaf extract impairs mitochondria by pro-oxidant activity in MDA-MB-231 and OVCAR-3 cancer cells
R Benot-Dominguez, MG Tupone, V Castelli… - Biomedicine & …, 2021 - Elsevier
Breast and ovarian cancers are the leading and fifth reason for tumor death among females,
respectively. Recently, many studies demonstrated antiproliferative activities of natural …
respectively. Recently, many studies demonstrated antiproliferative activities of natural …
Interleukin 8 mediates bcl‐xL‐induced enhancement of human melanoma cell dissemination and angiogenesis in a zebrafish xenograft model
C Gabellini, E Gómez‐Abenza… - … journal of cancer, 2018 - Wiley Online Library
The protein bcl‐xL is able to enhance the secretion of the proinflammatory chemokine
interleukin 8 (CXCL8) in human melanoma lines. In this study, we investigate whether the …
interleukin 8 (CXCL8) in human melanoma lines. In this study, we investigate whether the …
[HTML][HTML] L-methionine protects against oxidative stress and mitochondrial dysfunction in an in vitro model of Parkinson's disease
M Catanesi, L Brandolini, M d'Angelo, E Benedetti… - Antioxidants, 2021 - mdpi.com
Methionine is an aliphatic, sulfur-containing, essential amino acid that has been
demonstrated to have crucial roles in metabolism, innate immunity, and activation of …
demonstrated to have crucial roles in metabolism, innate immunity, and activation of …
[HTML][HTML] SOX2 boosts major tumor progression genes in prostate cancer and is a functional biomarker of lymph node metastasis
SOX2 boosts major tumor progression genes in prostate cancer and is a functional biomarker
of lymph node metastasis - PMC Back to Top Skip to main content NIH NLM Logo Access keys …
of lymph node metastasis - PMC Back to Top Skip to main content NIH NLM Logo Access keys …
[HTML][HTML] microRNA-378a-5p iS a novel positive regulator of melanoma progression
MG Tupone, S D'Aguanno, M Di Martile, E Valentini… - Oncogenesis, 2020 - nature.com
Evaluating the expression levels of miR-378a-5p both in a large melanoma patient cohort
from The Cancer Genome Atlas database and in melanoma patients from our Institute, we …
from The Cancer Genome Atlas database and in melanoma patients from our Institute, we …
[HTML][HTML] Melanoma-specific bcl-2 promotes a protumoral M2-like phenotype by tumor-associated macrophages
M Di Martile, V Farini, FM Consonni… - … for immunotherapy of …, 2020 - ncbi.nlm.nih.gov
Background A bidirectional crosstalk between tumor cells and the surrounding
microenvironment contributes to tumor progression and response to therapy. Our previous …
microenvironment contributes to tumor progression and response to therapy. Our previous …