Update on lymphadenectomy in early and advanced ovarian cancer

R Angioli, F Plotti, I Palaia, M Calcagno… - Current Opinion in …, 2008 - journals.lww.com
Systematic lymphadenectomy has a diagnostic value in early-stage ovarian cancer, thanks
to the possibility of accurate clinical staging. As up to 22% of women, who were presumed to …

Functional characterization of epithelial ovarian cancer histotypes by drug target based protein signaling activation mapping: implications for personalized cancer …

MI Sereni, E Baldelli, G Gambara, J Deng… - …, 2015 - Wiley Online Library
Epithelial ovarian carcinoma (EOC) is a deadly disease, with a 5‐year survival of 30%. The
aim of the study was to perform broad‐scale protein signaling activation mapping to …

[HTML][HTML] Intraoperative contact ultrasonography during open myomectomy for uterine fibroids

R Angioli, C Battista, C Terranova, MA Zullo, MI Sereni… - Fertility and sterility, 2010 - Elsevier
OBJECTIVE: To evaluate the benefit of intraoperative ultrasound applied directly to the
uterine serosa during surgery for uterine fibroids. DESIGN: Prospective study. SETTING …

A gastrointestinal stromal tumor presenting as a pelvic mass: a case report

R Angioli, C Battista, L Muzii… - Oncology …, 2009 - spandidos-publications.com
Gastrointestinal stromal tumors (GISTs) represent 0.1-1% of gastrointestinal malignancies.
They are commonly asymptomatic and found incidentally during laparoscopy, surgical …

[HTML][HTML] PD-L1 quantification across tumor types using the reverse phase protein microarray: implications for precision medicine

E Baldelli, KA Hodge, G Bellezza, NJ Shah… - … for Immunotherapy of …, 2021 - ncbi.nlm.nih.gov
Background Anti-programmed cell death protein 1 and programmed cell death ligand 1 (PD-
L1) agents are broadly used in first-line and second-line treatment across different tumor …

The challenge of preoperative identification of uterine myomas: is ultrasound trustworthy? A prospective cohort study

C Battista, S Capriglione, F Guzzo, D Luvero… - Archives of gynecology …, 2016 - Springer
Purpose To correlate preoperative ultrasound examination with intraoperative and anatomo-
pathological findings, including estimation of number, localization and size of uterine …

[HTML][HTML] Kinase-driven metabolic signalling as a predictor of response to carboplatin–paclitaxel adjuvant treatment in advanced ovarian cancers

MI Sereni, E Baldelli, G Gambara, A Ravaggi… - British Journal of …, 2017 - nature.com
Background: The biological mechanisms underlying early-and advanced-stage epithelial
ovarian cancers (EOCs) are still poorly understood. This study explored kinase-driven …

Reverse phase protein microarrays and their utility in drug development

MI Sereni, M Pierobon, R Angioli, EF Petricoin… - Target Identification and …, 2013 - Springer
The majority of human diseases, including cancer, are characterized by abnormal protein
function. Proteins regulate virtually every cellular process and exhibit multiple kinds of post …

Quantitative measurement of PDL1 expression across tumor types using laser capture microdissection and reverse phase protein microarray

E Baldelli, V Calvert, KA Hodge, MI Sereni, G Gambara… - Cancer Research, 2017 - AACR
Background: The efficacy of immunotherapy, including therapeutic strategies capable of
modulating innate/adaptive immune resistance, varies greatly across tumor types. As the …

Development of a quantitative PD-L1 assay using laser capture microdissection (LCM)-based reverse phase protein microarray (RPPA) workflow: Implications for …

M Pierobon, E Baldelli, KA Hodge, MI Sereni… - 2018 - ascopubs.org
35 Background: FDA approved IHC-based companion/complementary assays are routinely
used to measure PD-L1 for treatment selection. However, IHC cut-point values vary across …