Despite prophylaxis with immunosuppressive agents or a variety of other approaches, many
patients suffer from acute graft-versus-host disease (aGVHD) after allogeneic hematopoietic …

Celiac disease is a common systemic disorder that can have multiple hematologic
manifestations. Patients with celiac disease may present to hematologists for evaluation of …

Peripheral blood progenitor cell mobilization practices vary significantly among institutions.
Effective mobilization regimens include growth factor alone, chemotherapy and growth factor …

Recently, a gain-of-function MPL mutation, MPL W515L, was described in patients with
JAK2 V617F-negative myelofibrosis with myeloid metaplasia (MMM). To gain more …

Background In young adults with acute myeloid leukemia (AML), intensification of the
anthracycline dose during induction therapy has improved the rate of complete remission …

Pretreatment cytogenetics is a known predictor of outcome in hematologic malignancies.
However, its usefulness in adult acute lymphoblastic leukemia (ALL) is generally limited to …

An international collaboration was set up to prospectively evaluate the role of allogeneic
transplantation for adults with acute lymphoblastic leukemia (ALL) and compare autologous …

Most adults with acute lymphoblastic leukemia (ALL) who achieve complete remission (CR)
will relapse. We examined the outcome of 609 adults with recurring ALL, all of whom were …

We report the results of a phase III open-label, randomized, multicenter trial comparing
tacrolimus/methotrexate to cyclosporine/methotrexate for graft-versus-host disease (GVHD) …

The international acute lymphoblastic leukemia (ALL) study was designed to prospectively
define the optimal therapy for adults 60 years of age or younger with newly diagnosed ALL …