User profiles for "author:Mark Smolkin"

Mark Smolkin

University of Virginia
Verified email at virginia.edu
Cited by 4491

Immunotype and immunohistologic characteristics of tumor-infiltrating immune cells are associated with clinical outcome in metastatic melanoma

G Erdag, JT Schaefer, ME Smolkin, DH Deacon… - Cancer research, 2012 - AACR
Immune cells infiltrating the microenvironment of melanoma metastases may either limit or
promote tumor progression, but the characteristics that distinguish these effects are obscure …

Screening colonoscopies by primary care physicians: a meta-analysis

T Wilkins, B LeClair, M Smolkin, K Davies… - The Annals of Family …, 2009 - Annals Family Med
PURPOSE There is currently too few endoscopists to enact a national colorectal cancer
screening program with colonoscopy. Primary care physicians could play an important role …

Immunologic and clinical outcomes of a randomized phase II trial of two multipeptide vaccines for melanoma in the adjuvant setting

CL Slingluff Jr, GR Petroni, KA Chianese-Bullock… - Clinical Cancer …, 2007 - AACR
Purpose: Human melanoma cells express shared antigens recognized by CD8+ T
lymphocytes, the most common of which are melanocytic differentiation proteins and cancer …

Effect of Granulocyte/Macrophage Colony-Stimulating Factor on Circulating CD8+ and CD4+ T-Cell Responses to a Multipeptide Melanoma Vaccine: Outcome of a …

CL Slingluff Jr, GR Petroni, WC Olson, ME Smolkin… - Clinical Cancer …, 2009 - AACR
Purpose: Granulocyte/macrophage colony-stimulating factor (GM-CSF) administered locally
together with vaccines can augment T-cell responses in animal models. Human experience …

Prognostic value of albumin in patients with head and neck cancer

D Danan, DC Shonka Jr, Y Selman, Z Chow… - The …, 2016 - Wiley Online Library
Objectives/Hypothesis Albumin is an indicator of nutritional status and has been investigated
as a predictor of cancer survival and perioperative outcomes. This study investigated the …

PD-L1, PD-L2 and PD-1 expression in metastatic melanoma: Correlation with tumor-infiltrating immune cells and clinical outcome

JM Obeid, G Erdag, ME Smolkin, DH Deacon… - …, 2016 - Taylor & Francis
Therapeutic blockade of PD-1/PD-L1 can have dramatic therapeutic benefit in some
patients; however, the prognostic associations of PD-1 and its ligands, in the absence of …

Accuracy of assigned BI-RADS breast density category definitions

BT Nicholson, AP LoRusso, M Smolkin, VE Bovbjerg… - Academic radiology, 2006 - Elsevier
RATIONALE AND OBJECTIVES: Quantitative criteria for the Breast Imaging Reporting and
Data System (BI-RADS) mammographic density categories have recently been defined as< …

[HTML][HTML] Randomized multicenter trial of the effects of melanoma-associated helper peptides and cyclophosphamide on the immunogenicity of a multipeptide …

CL Slingluff Jr, GR Petroni… - Journal of clinical …, 2011 - ncbi.nlm.nih.gov
Purpose This multicenter randomized trial was designed to test whether melanoma-
associated helper peptides augment CD8+ T-cell responses to a melanoma vaccine and …

[HTML][HTML] Loss of the urothelial differentiation marker FOXA1 is associated with high grade, late stage bladder cancer and increased tumor proliferation

DJ DeGraff, PE Clark, JM Cates, H Yamashita… - PloS one, 2012 - journals.plos.org
Approximately 50% of patients with muscle-invasive bladder cancer (MIBC) develop
metastatic disease, which is almost invariably lethal. However, our understanding of …

Contribution of Burkholderia cenocepacia Flagella to Infectivity and Inflammation

TA Urban, A Griffith, AM Torok, ME Smolkin… - Infection and …, 2004 - Am Soc Microbiol
Burkholderia cenocepacia is an opportunistic pathogen that can cause severe lung
infections in cystic fibrosis patients. To understand the contribution of B. cenocepacia …