[HTML][HTML] Skin cancer classification via convolutional neural networks: systematic review of studies involving human experts
Background Multiple studies have compared the performance of artificial intelligence (AI)–
based models for automated skin cancer classification to human experts, thus setting the …
based models for automated skin cancer classification to human experts, thus setting the …
[HTML][HTML] Explainable artificial intelligence in skin cancer recognition: A systematic review
K Hauser, A Kurz, S Haggenmüller, RC Maron… - European Journal of …, 2022 - Elsevier
Background Due to their ability to solve complex problems, deep neural networks (DNNs)
are becoming increasingly popular in medical applications. However, decision-making by …
are becoming increasingly popular in medical applications. However, decision-making by …
Immune checkpoint blockade for unresectable or metastatic uveal melanoma: A systematic review
MV Heppt, T Steeb, JG Schlager, S Rosumeck… - Cancer treatment …, 2017 - Elsevier
Background The use of immune checkpoint blockade (ICB) for uveal melanoma (UM) is little
established. The aim of this review was to provide a comprehensive overview on the …
established. The aim of this review was to provide a comprehensive overview on the …
[HTML][HTML] Deep learning outperformed 136 of 157 dermatologists in a head-to-head dermoscopic melanoma image classification task
Background Recent studies have successfully demonstrated the use of deep-learning
algorithms for dermatologist-level classification of suspicious lesions by the use of excessive …
algorithms for dermatologist-level classification of suspicious lesions by the use of excessive …
[HTML][HTML] A convolutional neural network trained with dermoscopic images performed on par with 145 dermatologists in a clinical melanoma image classification task
Background Recent studies have demonstrated the use of convolutional neural networks
(CNNs) to classify images of melanoma with accuracies comparable to those achieved by …
(CNNs) to classify images of melanoma with accuracies comparable to those achieved by …
[HTML][HTML] Myositis and neuromuscular side-effects induced by immune checkpoint inhibitors
A Moreira, C Loquai, C Pföhler, KC Kähler… - European Journal of …, 2019 - Elsevier
Aim To characterise clinical presentation, laboratory and histopathologic characteristics and
assess the treatment and outcome of neuromuscular side-effects of checkpoint therapy …
assess the treatment and outcome of neuromuscular side-effects of checkpoint therapy …
[HTML][HTML] Prognostic factors and outcomes in metastatic uveal melanoma treated with programmed cell death-1 or combined PD-1/cytotoxic T-lymphocyte antigen-4 …
MV Heppt, L Heinzerling, KC Kähler… - European Journal of …, 2017 - Elsevier
Background Uveal melanoma (UM) is an ocular malignancy with high potential for
metastatic spread. In contrast to cutaneous melanoma, immunotherapy has not yet shown …
metastatic spread. In contrast to cutaneous melanoma, immunotherapy has not yet shown …
[HTML][HTML] Prognostic significance of BRAF and NRAS mutations in melanoma: a German study from routine care
MV Heppt, T Siepmann, J Engel, G Schubert-Fritschle… - BMC cancer, 2017 - Springer
Background Hotspot mutations of the oncogenes BRAF and NRAS are the most common
genetic alterations in cutaneous melanoma. Specific inhibitors of BRAF and MEK have …
genetic alterations in cutaneous melanoma. Specific inhibitors of BRAF and MEK have …
[HTML][HTML] Combining CNN-based histologic whole slide image analysis and patient data to improve skin cancer classification
J Höhn, E Krieghoff-Henning, TB Jutzi… - European Journal of …, 2021 - Elsevier
Background Clinicians and pathologists traditionally use patient data in addition to clinical
examination to support their diagnoses. Objectives We investigated whether a combination …
examination to support their diagnoses. Objectives We investigated whether a combination …
[HTML][HTML] IFN-gamma-induced PD-L1 expression in melanoma depends on p53 expression
A Thiem, S Hesbacher, H Kneitz, T di Primio… - Journal of Experimental …, 2019 - Springer
Background Immune checkpoint inhibition and in particular anti-PD-1 immunotherapy have
revolutionized the treatment of advanced melanoma. In this regard, higher tumoral PD-L1 …
revolutionized the treatment of advanced melanoma. In this regard, higher tumoral PD-L1 …