Bioconductor is an open-source, open-development software project for the analysis and
comprehension of high-throughput data in genomics and molecular biology. The project …

Recent technological advancements have enabled the profiling of a large number of
genome-wide features in individual cells. However, single-cell data present unique …

It is widely agreed that the flowers of hermaphrodite plants evolve in response to selection
acting simultaneously through male and female sexual functions, but we know very little …

We describe Bioconductor infrastructure for representing and computing on annotated
genomic ranges and integrating genomic data with the statistical computing features of R …

Determining whether seed production is pollen limited has been an area of intensive
empirical study over the last two decades. Yet current evidence does not allow satisfactory …

Background Bacterial vaginosis (BV) is a common condition that is associated with
numerous adverse health outcomes and is characterized by poorly understood changes in …

Recent studies have demonstrated that MyoD initiates a feed-forward regulation of skeletal
muscle gene expression, predicting that MyoD binds directly to many genes expressed …

ShortRead is a package for input, quality assessment, manipulation and output of high-
throughput sequencing data. ShortRead is provided in the R and Bioconductor …

VariantAnnotation is an R/Bioconductor package for the exploration and annotation of
genetic variants. Capabilities exist for reading, writing and filtering variant call format (VCF) …

To the Editor: The microbiome has emerged as a key aspect of human biology and has been
implicated in many disease etiologies. Shotgun metagenomic sequencing is an approach …