User profiles for "author:Meggy Suarez-Carmona"
Meggy Suarez-CarmonaGerman Cancer Research Center Verified email at dkfz-heidelberg.de Cited by 2201 |
EMT and inflammation: inseparable actors of cancer progression
M Suarez‐Carmona, J Lesage, D Cataldo… - Molecular …, 2017 - Wiley Online Library
Tumors can be depicted as wounds that never heal, and are infiltrated by a large array of
inflammatory and immune cells. Tumor‐associated chronic inflammation is a hallmark of …
inflammatory and immune cells. Tumor‐associated chronic inflammation is a hallmark of …
Defensins:“Simple” antimicrobial peptides or broad-spectrum molecules?
M Suarez-Carmona, P Hubert, P Delvenne… - Cytokine & growth factor …, 2015 - Elsevier
Small cationic peptides highly conserved in vertebrates, both α-and β-defensins were
primarily identified as anti-microbial compounds involved in innate immunity. While human α …
primarily identified as anti-microbial compounds involved in innate immunity. While human α …
[PDF][PDF] Tumoral immune cell exploitation in colorectal cancer metastases can be targeted effectively by anti-CCR5 therapy in cancer patients
N Halama, I Zoernig, A Berthel, C Kahlert, F Klupp… - Cancer cell, 2016 - cell.com
The immune response influences the clinical course of colorectal cancer (CRC). Analyzing
the invasive margin of human CRC liver metastases, we identified a mechanism of immune …
the invasive margin of human CRC liver metastases, we identified a mechanism of immune …
Radiotherapy orchestrates natural killer cell dependent antitumor immune responses through CXCL8
T Walle, JA Kraske, B Liao, B Lenoir, C Timke… - Science …, 2022 - science.org
Radiotherapy is a mainstay cancer therapy whose antitumor effects partially depend on T
cell responses. However, the role of Natural Killer (NK) cells in radiotherapy remains …
cell responses. However, the role of Natural Killer (NK) cells in radiotherapy remains …
Topography of cancer-associated immune cells in human solid tumors
Lymphoid and myeloid cells are abundant in the tumor microenvironment, can be quantified
by immunohistochemistry and shape the disease course of human solid tumors. Yet, there is …
by immunohistochemistry and shape the disease course of human solid tumors. Yet, there is …
In Silico Modeling of Immunotherapy and Stroma-Targeting Therapies in Human Colorectal Cancer
Despite the fact that the local immunological microenvironment shapes the prognosis of
colorectal cancer, immunotherapy has shown no benefit for the vast majority of colorectal …
colorectal cancer, immunotherapy has shown no benefit for the vast majority of colorectal …
Tissue factor induced by epithelial–mesenchymal transition triggers a procoagulant state that drives metastasis of circulating tumor cells
M Bourcy, M Suarez-Carmona, J Lambert, ME Francart… - Cancer research, 2016 - AACR
Epithelial–mesenchymal transition (EMT) is prominent in circulating tumor cells (CTC), but
how it influences metastatic spread in this setting is obscure. Insofar as blood provides a …
how it influences metastatic spread in this setting is obscure. Insofar as blood provides a …
[HTML][HTML] Combined inhibition of CXCL12 and PD-1 in MSS colorectal and pancreatic cancer: modulation of the microenvironment and clinical effects
M Suarez-Carmona, A Williams… - … for Immunotherapy of …, 2021 - ncbi.nlm.nih.gov
Background Immunotherapy in microsatellite stable colorectal or pancreatic cancer has not
shown promising results. It has been hypothesized that targeting immunosuppressive …
shown promising results. It has been hypothesized that targeting immunosuppressive …
Carcinogenic HPV infection in the cervical squamo‐columnar junction
J Mirkovic, BE Howitt, P Roncarati… - The Journal of …, 2015 - Wiley Online Library
Recent studies have suggested the involvement of a unique population of cells at the
cervical squamo‐columnar junction (SCJ) in the pathogenesis of early (squamous …
cervical squamo‐columnar junction (SCJ) in the pathogenesis of early (squamous …
Soluble factors regulated by epithelial–mesenchymal transition mediate tumour angiogenesis and myeloid cell recruitment
M Suarez‐Carmona, M Bourcy, J Lesage… - The Journal of …, 2015 - Wiley Online Library
Epithelial–mesenchymal transition (EMT) programmes provide cancer cells with invasive
and survival capacities that might favour metastatic dissemination. Whilst signalling …
and survival capacities that might favour metastatic dissemination. Whilst signalling …