The serial endosymbiosis theory is a favored model for explaining the origin of mitochondria,
a defining event in the evolution of eukaryotic cells. As usually described, this theory posits …

▪ Abstract Recent results from ancestral (minimally derived) protists testify to the tremendous
diversity of the mitochondrial genome in various eukaryotic lineages, but also reinforce the …

Summary Pseudouridine (5-ribosyluracil) is a ubiquitous yet enigmatic constituent of
structural RNAs (transfer, ribosomal, small nuclear, and small nucleolar). Although …

We sequenced the 29,751-base genome of the severe acute respiratory syndrome (SARS)–
associated coronavirus known as the Tor2 isolate. The genome sequence reveals that this …

Classification of objects is an important area of research and application in a variety of fields.
In the presence of full knowledge of the underlying probabilities, Bayes decision theory …

Viewed through the lens of the genome it contains, the mitochondrion is of unquestioned
bacterial ancestry, originating from within the bacterial phylum α-Proteobacteria …

Mitochondria, organelles specialized in energy conservation reactions in eukaryotic cells,
have evolved from eubacteria-like endo-symbionts 1–3 whose closest known relatives are …

Fluorouracil (5FU) and oxaliplatin are standard therapy for metastatic colorectal cancer
(CRC), but the development of chemoresistance is inevitable. Because cancer stem cells …

Mitochondria have their own genetic system–a vestigial genome originating from an
endosymbiotic α-proteobacterial ancestor. The genetic function of mitochondrial DNA …

Publisher Summary This chapter highlights endosymbiont hypothesis. All contemporary
genomes (including those of plastids and mitochondria) ultimately derive from a single …