User profiles for "author:Michael Gray"
Michael W. GrayProfessor Emeritus, Dept. of Biochemistry & Molecular Biology, Dalhousie University Verified email at dal.ca Cited by 30921 |
Mitochondrial evolution
The serial endosymbiosis theory is a favored model for explaining the origin of mitochondria,
a defining event in the evolution of eukaryotic cells. As usually described, this theory posits …
a defining event in the evolution of eukaryotic cells. As usually described, this theory posits …
Mitochondrial genome evolution and the origin of eukaryotes
▪ Abstract Recent results from ancestral (minimally derived) protists testify to the tremendous
diversity of the mitochondrial genome in various eukaryotic lineages, but also reinforce the …
diversity of the mitochondrial genome in various eukaryotic lineages, but also reinforce the …
[PDF][PDF] Pseudouridine in RNA: what, where, how, and why
M Charette, MW Gray - IUBMB life, 2000 - bpg.utoledo.edu
Summary Pseudouridine (5-ribosyluracil) is a ubiquitous yet enigmatic constituent of
structural RNAs (transfer, ribosomal, small nuclear, and small nucleolar). Although …
structural RNAs (transfer, ribosomal, small nuclear, and small nucleolar). Although …
The genome sequence of the SARS-associated coronavirus
We sequenced the 29,751-base genome of the severe acute respiratory syndrome (SARS)–
associated coronavirus known as the Tor2 isolate. The genome sequence reveals that this …
associated coronavirus known as the Tor2 isolate. The genome sequence reveals that this …
A fuzzy k-nearest neighbor algorithm
JM Keller, MR Gray, JA Givens - IEEE transactions on systems …, 1985 - ieeexplore.ieee.org
Classification of objects is an important area of research and application in a variety of fields.
In the presence of full knowledge of the underlying probabilities, Bayes decision theory …
In the presence of full knowledge of the underlying probabilities, Bayes decision theory …
Mitochondrial evolution
MW Gray - Cold Spring Harbor perspectives in biology, 2012 - cshperspectives.cshlp.org
Viewed through the lens of the genome it contains, the mitochondrion is of unquestioned
bacterial ancestry, originating from within the bacterial phylum α-Proteobacteria …
bacterial ancestry, originating from within the bacterial phylum α-Proteobacteria …
An ancestral mitochondrial DNA resembling a eubacterial genome in miniature
Mitochondria, organelles specialized in energy conservation reactions in eukaryotic cells,
have evolved from eubacteria-like endo-symbionts 1–3 whose closest known relatives are …
have evolved from eubacteria-like endo-symbionts 1–3 whose closest known relatives are …
Chemoresistant colorectal cancer cells, the cancer stem cell phenotype, and increased sensitivity to insulin-like growth factor-I receptor inhibition
NA Dallas, L Xia, F Fan, MJ Gray, P Gaur, G Van Buren… - Cancer research, 2009 - AACR
Fluorouracil (5FU) and oxaliplatin are standard therapy for metastatic colorectal cancer
(CRC), but the development of chemoresistance is inevitable. Because cancer stem cells …
(CRC), but the development of chemoresistance is inevitable. Because cancer stem cells …
Mitochondrial genomes: anything goes
Mitochondria have their own genetic system–a vestigial genome originating from an
endosymbiotic α-proteobacterial ancestor. The genetic function of mitochondrial DNA …
endosymbiotic α-proteobacterial ancestor. The genetic function of mitochondrial DNA …
The endosymbiont hypothesis revisited
MW Gray - International review of cytology, 1992 - Elsevier
Publisher Summary This chapter highlights endosymbiont hypothesis. All contemporary
genomes (including those of plastids and mitochondria) ultimately derive from a single …
genomes (including those of plastids and mitochondria) ultimately derive from a single …