User profiles for "author:Mihir D Wechalekar"

Mihir D Wechalekar

Flinders University
Verified email at sa.gov.au
Cited by 2644

Multinational evidence-based recommendations for the diagnosis and management of gout: integrating systematic literature review and expert opinion of a broad …

F Sivera, M Andrés, L Carmona, ASR Kydd… - Annals of the …, 2014 - ard.bmj.com
We aimed to develop evidence-based multinational recommendations for the diagnosis and
management of gout. Using a formal voting process, a panel of 78 international …

Non‐steroidal anti‐inflammatory drugs for acute gout

CMPG van Durme, MD Wechalekar… - Cochrane Database …, 2014 - cochranelibrary.com
Background Gout is an inflammatory arthritis that is characterised by the deposition of
monosodium urate crystals in synovial fluid and other tissues. The natural history of articular …

Colchicine for acute gout

I van Echteld, MD Wechalekar… - Cochrane database …, 2014 - cochranelibrary.com
Background This is an update of a Cochrane review first published in 2006. Gout is one of
the most common rheumatic diseases worldwide. Despite the use of colchicine as one of the …

[HTML][HTML] Th17 and Th22 cells in psoriatic arthritis and psoriasis

H Benham, P Norris, J Goodall, MD Wechalekar… - Arthritis research & …, 2013 - Springer
Introduction The aim of this study was to characterize interleukin 17 (IL-17) and interleukin
22 (IL-22) producing cells in peripheral blood (PB), skin, synovial fluid (SF) and synovial …

Fish oil in recent onset rheumatoid arthritis: a randomised, double-blind controlled trial within algorithm-based drug use

SM Proudman, MJ James, LD Spargo… - Annals of the …, 2015 - ard.bmj.com
Background The effects of fish oil (FO) in rheumatoid arthritis (RA) have not been examined
in the context of contemporary treatment of early RA. This study examined the effects of high …

[HTML][HTML] Immune checkpoint inhibitor PD-1 pathway is down-regulated in synovium at various stages of rheumatoid arthritis disease progression

Y Guo, AM Walsh, M Canavan, MD Wechalekar… - PloS one, 2018 - journals.plos.org
Immune checkpoint blockade with therapeutic anti-cytotoxic T lymphocyte-associated
antigen (CTLA)-4 (Ipilimumab) and anti-programmed death (PD)-1 (Nivolumab and …

[HTML][HTML] Integrative analysis reveals CD38 as a therapeutic target for plasma cell-rich pre-disease and established rheumatoid arthritis and systemic lupus …

S Cole, A Walsh, X Yin, MD Wechalekar… - Arthritis research & …, 2018 - Springer
Background Plasmablasts and plasma cells play a key role in many autoimmune diseases,
such as rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). This study was …

CD40L-dependent pathway is active at various stages of rheumatoid arthritis disease progression

Y Guo, AM Walsh, U Fearon, MD Smith… - The Journal of …, 2017 - journals.aai.org
Abstract The inflammatory CD40–CD40L pathway is implicated in various autoimmune
diseases, but the activity status of this pathway in various stages of rheumatoid arthritis (RA) …

[HTML][HTML] Artificial intelligence and the future of radiographic scoring in rheumatoid arthritis: a viewpoint

A Bird, L Oakden-Rayner, C McMaster… - Arthritis Research & …, 2022 - Springer
Rheumatoid arthritis is an autoimmune condition that predominantly affects the synovial
joints, causing joint destruction, pain, and disability. Historically, the standard for measuring …

Interleukin‐1 inhibitors for acute gout

F Sivera, MD Wechalekar, M Andrés… - Cochrane Database …, 2014 - cochranelibrary.com
Background Acute gout flares cause significant pain and disability and it is important to
provide quick and effective pain relief. Traditional options for managing acute flares include …