User profiles for "author:Ming O. Li"

Ming O Li

Memorial Sloan Kettering Cancer Center
Verified email at mskcc.org
Cited by 24502

Transforming growth factor-β regulation of immune responses

MO Li, YY Wan, S Sanjabi, AKL Robertson… - Annu. Rev …, 2006 - annualreviews.org
Transforming growth factor-β (TGF-β) is a potent regulatory cytokine with diverse effects on
hemopoietic cells. The pivotal function of TGF-β in the immune system is to maintain …

[HTML][HTML] TGF-β: a master of all T cell trades

MO Li, RA Flavell - Cell, 2008 - cell.com
A functional adaptive immune system depends on a diverse and self-tolerant population of T
lymphocytes that are generated in the thymus and maintained in the peripheral lymphoid …

[HTML][HTML] Contextual regulation of inflammation: a duet by transforming growth factor-β and interleukin-10

MO Li, RA Flavell - Immunity, 2008 - cell.com
Transforming growth factor-β (TGF-β) and interleukin-10 (IL-10) are regulatory cytokines with
pleiotropic roles in the immune system. The prominent function of TGF-β is to maintain T cell …

The cellular and molecular origin of tumor-associated macrophages

RA Franklin, W Liao, A Sarkar, MV Kim, MR Bivona… - Science, 2014 - science.org
Long recognized as an evolutionarily ancient cell type involved in tissue homeostasis and
immune defense against pathogens, macrophages are being rediscovered as regulators of …

[HTML][HTML] Transforming growth factor-β controls development, homeostasis, and tolerance of T cells by regulatory T cell-dependent and-independent mechanisms

MO Li, S Sanjabi, RA Flavell - Immunity, 2006 - cell.com
The role of transforming growth factor-β (TGF-β) in inhibiting T cell functions has been
studied with dominant-negative TGF-β receptor transgenic models; however, the full impact …

[PDF][PDF] T cell-produced transforming growth factor-β1 controls T cell tolerance and regulates Th1-and Th17-cell differentiation

MO Li, YY Wan, RA Flavell - Immunity, 2007 - cell.com
TGF-β1 is a regulatory cytokine with a pleiotropic role in immune responses. TGF-β1 is
widely expressed in leukocytes and stromal cells. However, the functions of TGF-β1 …

[HTML][HTML] Tumor immune microenvironment characterization in clear cell renal cell carcinoma identifies prognostic and immunotherapeutically relevant messenger RNA …

Y Şenbabaoğlu, RS Gejman, AG Winer, M Liu… - Genome biology, 2016 - Springer
Background Tumor-infiltrating immune cells have been linked to prognosis and response to
immunotherapy; however, the levels of distinct immune cell subsets and the signals that …

Neuropilin 1 is expressed on thymus-derived natural regulatory T cells, but not mucosa-generated induced Foxp3+ T reg cells

JM Weiss, AM Bilate, M Gobert, Y Ding… - Journal of Experimental …, 2012 - rupress.org
Foxp3 activity is essential for the normal function of the immune system. Two types of
regulatory T (T reg) cells express Foxp3, thymus-generated natural T reg (nT reg) cells, and …

Aerobic glycolysis promotes T helper 1 cell differentiation through an epigenetic mechanism

M Peng, N Yin, S Chhangawala, K Xu, CS Leslie… - Science, 2016 - science.org
Aerobic glycolysis (the Warburg effect) is a metabolic hallmark of activated T cells and has
been implicated in augmenting effector T cell responses, including expression of the …

Foxo proteins cooperatively control the differentiation of Foxp3+ regulatory T cells

W Ouyang, O Beckett, Q Ma, J Paik, RA DePinho… - Nature …, 2010 - nature.com
CD4+ regulatory T cells (Treg cells) characterized by expression of the transcription factor
Foxp3 have a pivotal role in maintaining immunological tolerance. Here we show that mice …