User profiles for "author:Mira Ayadi"

Mira Ayadi

IntegraGen, an OncoDNA group company
Verified email at integragen.com
Cited by 2743

[HTML][HTML] Gene expression classification of colon cancer into molecular subtypes: characterization, validation, and prognostic value

L Marisa, A de Reyniès, A Duval, J Selves… - PLoS …, 2013 - journals.plos.org
Background Colon cancer (CC) pathological staging fails to accurately predict recurrence,
and to date, no gene expression signature has proven reliable for prognosis stratification in …

[HTML][HTML] Distinct epigenetic landscapes underlie the pathobiology of pancreatic cancer subtypes

G Lomberk, Y Blum, R Nicolle, A Nair… - Nature …, 2018 - nature.com
Recent studies have offered ample insight into genome-wide expression patterns to define
pancreatic ductal adenocarcinoma (PDAC) subtypes, although there remains a lack of …

[HTML][HTML] Review of prognostic expression markers for clear cell renal cell carcinoma

F Petitprez, M Ayadi, AL De Reyniès… - Frontiers in …, 2021 - frontiersin.org
Context: The number of prognostic markers for clear cell renal cell carcinoma (ccRCC) has
been increasing regularly over the last 15 years, without being integrated and compared …

[PDF][PDF] Identification of four immune subtypes characterized by distinct composition and functions of tumor microenvironment in intrahepatic cholangiocarcinoma

S Job, D Rapoud, A Dos Santos, P Gonzalez… - …, 2020 - Wiley Online Library
Background and Aims Intrahepatic cholangiocarcinoma (ICC) is a severe malignant tumor in
which the standard therapies are mostly ineffective. The biological significance of the …

[PDF][PDF] Pancreatic adenocarcinoma therapeutic targets revealed by tumor-stroma cross-talk analyses in patient-derived xenografts

R Nicolle, Y Blum, L Marisa, C Loncle, O Gayet… - Cell reports, 2017 - cell.com
Preclinical models based on patient-derived xenografts have remarkable specificity in
distinguishing transformed human tumor cells from non-transformed murine stromal cells …

[HTML][HTML] Dissecting heterogeneity in malignant pleural mesothelioma through histo-molecular gradients for clinical applications

Y Blum, C Meiller, L Quetel, N Elarouci, M Ayadi… - Nature …, 2019 - nature.com
Malignant pleural mesothelioma (MPM) is recognized as heterogeneous based both on
histology and molecular profiling. Histology addresses inter-tumor and intra-tumor …

[HTML][HTML] Arabidopsis HAF2 gene encoding TATA-binding protein (TBP)-associated factor TAF1, is required to integrate light signals to regulate gene expression and …

C Bertrand, M Benhamed, YF Li, M Ayadi… - Journal of Biological …, 2005 - ASBMB
Plant growth and development are sensitive to light. Light-responsive DNA-binding
transcription factors have been functionally identified. However, how transcription initiation …

[HTML][HTML] The murine Microenvironment Cell Population counter method to estimate abundance of tissue-infiltrating immune and stromal cell populations in murine …

F Petitprez, S Levy, CM Sun, M Meylan, C Linhard… - Genome medicine, 2020 - Springer
Quantifying tissue-infiltrating immune and stromal cells provides clinically relevant
information for various diseases. While numerous methods can quantify immune or stromal …

[HTML][HTML] Establishment of a pancreatic adenocarcinoma molecular gradient (PAMG) that predicts the clinical outcome of pancreatic cancer

R Nicolle, Y Blum, P Duconseil, C Vanbrugghe… - …, 2020 - thelancet.com
Background A significant gap in pancreatic ductal adenocarcinoma (PDAC) patient's care is
the lack of molecular parameters characterizing tumours and allowing a personalized …

Performance of next-generation sequencing for the detection of microsatellite instability in colorectal cancer with deficient DNA mismatch repair

T Ratovomanana, R Cohen, M Svrcek, F Renaud… - Gastroenterology, 2021 - Elsevier
Background & Aims Next-generation sequencing (NGS) was recently approved by the
United States Food and Drug Administration to detect microsatellite instability (MSI) arising …