User profiles for "author:Nadine van Montfoort"
 | Nadine van MontfoortGroup leader Verified email at lumc.nl Cited by 2144 |
Immunotherapeutic potential of TGF-β inhibition and oncolytic viruses
C Groeneveldt, T van Hall, SH van der Burg… - Trends in …, 2020 - cell.com
In cancer immunotherapy, a patient's own immune system is harnessed against cancer.
Immune checkpoint inhibitors release the brakes on tumor-reactive T cells and, therefore …
Immune checkpoint inhibitors release the brakes on tumor-reactive T cells and, therefore …
[HTML][HTML] Understanding MHC class I presentation of viral antigens by human dendritic cells as a basis for rational design of therapeutic vaccines
N van Montfoort, E van der Aa… - Frontiers in immunology, 2014 - frontiersin.org
Effective viral clearance requires the induction of virus-specific CD8+ cytotoxic T
lymphocytes (CTL). Since dendritic cells (DC) have a central role in initiating and shaping …
lymphocytes (CTL). Since dendritic cells (DC) have a central role in initiating and shaping …
BDCA3+ CLEC9A+ human dendritic cell function and development
E van der Aa, N van Montfoort, AM Woltman - Seminars in cell & …, 2015 - Elsevier
Dendritic cells (DC) are the most potent antigen presenting cells (APC). They comprise a
family of different subsets and play an essential role in the induction and regulation of …
family of different subsets and play an essential role in the induction and regulation of …
[PDF][PDF] NKG2A blockade potentiates CD8 T cell immunity induced by cancer vaccines
N van Montfoort, L Borst, MJ Korrer, M Sluijter… - Cell, 2018 - cell.com
Tumor-infiltrating CD8 T cells were found to frequently express the inhibitory receptor
NKG2A, particularly in immune-reactive environments and after therapeutic cancer …
NKG2A, particularly in immune-reactive environments and after therapeutic cancer …
[HTML][HTML] Cellular oxidative stress response controls the antiviral and apoptotic programs in dengue virus-infected dendritic cells
D Olagnier, S Peri, C Steel, N van Montfoort… - PLoS …, 2014 - journals.plos.org
Dengue virus (DENV) is a re-emerging arthropod borne flavivirus that infects more than 300
million people worldwide, leading to 50,000 deaths annually. Because dendritic cells (DC) …
million people worldwide, leading to 50,000 deaths annually. Because dendritic cells (DC) …
Antigen storage compartments in mature dendritic cells facilitate prolonged cytotoxic T lymphocyte cross-priming capacity
N van Montfoort, MG Camps, S Khan… - Proceedings of the …, 2009 - National Acad Sciences
Dendritic cells (DCs) are crucial for priming of naive CD8+ T lymphocytes to exogenous
antigens, so-called “cross-priming.” We report that exogenous protein antigen can be …
antigens, so-called “cross-priming.” We report that exogenous protein antigen can be …
A regression model with unexplained residuals was preferred in the analysis of the fetal origins of adult diseases hypothesis
MG Keijzer-Veen, AM Euser, N van Montfoort… - Journal of clinical …, 2005 - Elsevier
BACKGROUND AND OBJECTIVE: A continued controversy exists whether the assessment
of the influence of low birth weight on adult blood pressure necessitates adjustment for adult …
of the influence of low birth weight on adult blood pressure necessitates adjustment for adult …
Antigen processing by nardilysin and thimet oligopeptidase generates cytotoxic T cell epitopes
JH Kessler, S Khan, U Seifert, S Le Gall, KM Chow… - Nature …, 2011 - nature.com
Cytotoxic T lymphocytes (CTLs) recognize peptides presented by HLA class I molecules on
the cell surface. The C terminus of these CTL epitopes is considered to be produced by the …
the cell surface. The C terminus of these CTL epitopes is considered to be produced by the …
Immune complex-loaded dendritic cells are superior to soluble immune complexes as antitumor vaccine
DH Schuurhuis, N van Montfoort… - The Journal of …, 2006 - journals.aai.org
Dendritic cells (DCs) play an important role in the induction of T cell responses. FcγRs,
expressed on DCs, facilitate the uptake of complexed Ag, resulting in efficient MHC class I …
expressed on DCs, facilitate the uptake of complexed Ag, resulting in efficient MHC class I …
[HTML][HTML] Dendritic cell vaccination and CD40-agonist combination therapy licenses T cell-dependent antitumor immunity in a pancreatic carcinoma murine model
SP Lau, N van Montfoort, P Kinderman… - … for immunotherapy of …, 2020 - ncbi.nlm.nih.gov
Background Pancreatic ductal adenocarcinoma (PDAC) is notoriously resistant to treatment
including checkpoint-blockade immunotherapy. We hypothesized that a bimodal treatment …
including checkpoint-blockade immunotherapy. We hypothesized that a bimodal treatment …