[HTML][HTML] Hemorrhage-activated NRF2 in tumor-associated macrophages drives cancer growth, invasion, and immunotherapy resistance

DJ Schaer, N Schulthess-Lutz… - The Journal of …, 2024 - Am Soc Clin Investig
Microscopic hemorrhage is a common aspect of cancers, yet its potential role as an
independent factor influencing both cancer progression and therapeutic response is largely …

[HTML][HTML] MyD88-TLR4-dependent choroid plexus activation precedes perilesional inflammation and secondary brain edema in a mouse model of intracerebral …

K Akeret, RM Buzzi, BR Thomson… - Journal of …, 2022 - Springer
Background The functional neurological outcome of patients with intracerebral hemorrhage
(ICH) strongly relates to the degree of secondary brain injury (ICH-SBI) evolving within days …

[HTML][HTML] Antibody-induced erythrophagocyte reprogramming of Kupffer cells prevents anti-CD40 cancer immunotherapy-associated liver toxicity

M Pfefferlé, IL Dubach, RM Buzzi, E Dürst… - … for Immunotherapy of …, 2023 - ncbi.nlm.nih.gov
Background Agonistic anti-CD40 monoclonal antibodies (mAbs) have emerged as
promising immunotherapeutic compounds with impressive antitumor effects in mouse …

Supplementary Methods (detailed procedures and protocols)

M Pfefferlé, IL Dubach, RM Buzzi, E Dürst… - jitc.bmj.com
C57BL/6J (JAXTM strain) mice were obtained from Charles River Laboratories. Ms4a3Cre
mice were obtained from Dr. Florent Ginhoux (SingHealth and Duke NUS, Singapore)[1] and …

[CITATION][C] MyD88-TLR4-dependent choroid plexus activation precedes perilesional inflammation and secondary brain edema in a mouse model of intracerebral …

K Akeret, R Buzzi, B Thomson, N Schwendinger… - Brain and Spine, 2023 - Elsevier