User profiles for "author:Neha Chopra"

Dr Neha Chopra

Spine Service, University of New South Wales
Verified email at ad.unsw.edu.au
Cited by 59

[HTML][HTML] COVID-19 prevalence and mortality in patients with cancer and the effect of primary tumour subtype and patient demographics: a prospective cohort study

LYW Lee, JB Cazier, T Starkey, SEW Briggs… - The Lancet …, 2020 - thelancet.com
Background Patients with cancer are purported to have poor COVID-19 outcomes. However,
cancer is a heterogeneous group of diseases, encompassing a spectrum of tumour …

[HTML][HTML] Gut-disc axis: A cause of intervertebral disc degeneration and low back pain?

W Li, K Lai, N Chopra, Z Zheng, A Das… - European Spine Journal, 2022 - Springer
Purpose Low back pain (LBP), a widely prevalent and costly disease around the world, is
mainly caused by intervertebral disc (IVD) degeneration (IDD). Although numerous factors …

[HTML][HTML] Homologous recombination DNA repair deficiency and PARP inhibition activity in primary triple negative breast cancer

N Chopra, H Tovey, A Pearson, R Cutts, C Toms… - Nature …, 2020 - nature.com
Triple negative breast cancer (TNBC) encompasses molecularly different subgroups, with a
subgroup harboring evidence of defective homologous recombination (HR) DNA repair …

Assessment of molecular relapse detection in early-stage breast cancer

I Garcia-Murillas, N Chopra, I Comino-Méndez… - JAMA …, 2019 - jamanetwork.com
Importance Current treatment cures most cases of early-stage, primary breast cancer.
However, better techniques are required to identify which patients are at risk of relapse …

Clinical portrait of the SARS-CoV-2 epidemic in European patients with cancer

DJ Pinato, A Zambelli, J Aguilar-Company, M Bower… - Cancer discovery, 2020 - AACR
The SARS-CoV-2 pandemic significantly affected oncology practice across the globe. There
is uncertainty as to the contribution of patients' demographics and oncologic features to …

Outcomes of the SARS-CoV-2 omicron (B. 1.1. 529) variant outbreak among vaccinated and unvaccinated patients with cancer in Europe: results from the …

DJ Pinato, D Ferrante, G Hanbury, M Bower… - The Lancet …, 2022 - thelancet.com
Summary Background The omicron (B. 1.1. 529) variant of SARS-CoV-2 is highly
transmissible and escapes vaccine-induced immunity. We aimed to describe outcomes due …

Mortality among adults with cancer undergoing chemotherapy or immunotherapy and infected with COVID-19

C Várnai, C Palles, R Arnold, HM Curley… - JAMA network …, 2022 - jamanetwork.com
Importance Large cohorts of patients with active cancers and COVID-19 infection are
needed to provide evidence of the association of recent cancer treatment and cancer type …

Phase I Trial of the PARP Inhibitor Olaparib and AKT Inhibitor Capivasertib in Patients with BRCA1/2- and Non–BRCA1/2-Mutant Cancers

TA Yap, R Kristeleit, V Michalarea, SJ Pettitt, JSJ Lim… - Cancer discovery, 2020 - AACR
Preclinical studies have demonstrated synergy between PARP and PI3K/AKT pathway
inhibitors in BRCA1 and BRCA2 (BRCA1/2)–deficient and BRCA1/2-proficient tumors. We …

[HTML][HTML] Blood-spinal cord barrier: its role in spinal disorders and emerging therapeutic strategies

N Chopra, S Menounos, JP Choi, PM Hansbro… - NeuroSci, 2021 - mdpi.com
The blood-spinal cord barrier (BSCB) has been long thought of as a functional equivalent to
the blood-brain barrier (BBB), restricting blood flow into the spinal cord. The spinal cord is …

Prevalence and impact of COVID-19 sequelae on treatment and survival of patients with cancer who recovered from SARS-CoV-2 infection: evidence from the …

DJ Pinato, J Tabernero, M Bower, L Scotti… - The Lancet …, 2021 - thelancet.com
Background The medium-term and long-term impact of COVID-19 in patients with cancer is
not yet known. In this study, we aimed to describe the prevalence of COVID-19 sequelae …