User profiles for "author:Philippe Joubert"
Philippe JoubertUniversité Laval Verified email at ulaval.ca Cited by 7622 |
Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes
Although several lung cancer susceptibility loci have been identified, much of the heritability
for lung cancer remains unexplained. Here 14,803 cases and 12,262 controls of European …
for lung cancer remains unexplained. Here 14,803 cases and 12,262 controls of European …
[HTML][HTML] Single-cell spatial landscapes of the lung tumour immune microenvironment
Single-cell technologies have revealed the complexity of the tumour immune
microenvironment with unparalleled resolution,,,,,,,–. Most clinical strategies rely on …
microenvironment with unparalleled resolution,,,,,,,–. Most clinical strategies rely on …
New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries
Reduced lung function predicts mortality and is key to the diagnosis of chronic obstructive
pulmonary disease (COPD). In a genome-wide association study in 400,102 individuals of …
pulmonary disease (COPD). In a genome-wide association study in 400,102 individuals of …
Role of airway smooth muscle in airway remodeling
P Joubert, Q Hamid - Journal of allergy and clinical immunology, 2005 - jacionline.org
IL-4, IL-5, and IL-13. The expression of CC chemokine receptors, including CCR1 and
CCR3, was reported recently in ASMCs (Figs 7 and 8). These 2 chemokine receptors have …
CCR3, was reported recently in ASMCs (Figs 7 and 8). These 2 chemokine receptors have …
[PDF][PDF] MEK inhibition overcomes chemoimmunotherapy resistance by inducing CXCL10 in cancer cells
E Limagne, L Nuttin, M Thibaudin, E Jacquin… - Cancer Cell, 2022 - cell.com
Chemotherapy with anti PD-1/PD-L1 antibodies has become the standard of care for
patients with metastatic non-small cell lung cancer (mNSCLC). Using lung tumor models …
patients with metastatic non-small cell lung cancer (mNSCLC). Using lung tumor models …
Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets
Chronic obstructive pulmonary disease (COPD) is characterized by reduced lung function
and is the third leading cause of death globally. Through genome-wide association …
and is the third leading cause of death globally. Through genome-wide association …
Genomic and evolutionary classification of lung cancer in never smokers
Lung cancer in never smokers (LCINS) is a common cause of cancer mortality but its
genomic landscape is poorly characterized. Here high-coverage whole-genome sequencing …
genomic landscape is poorly characterized. Here high-coverage whole-genome sequencing …
Cross-reactivity between tumor MHC class I–restricted antigens and an enterococcal bacteriophage
Intestinal microbiota have been proposed to induce commensal-specific memory T cells that
cross-react with tumor-associated antigens. We identified major histocompatibility complex …
cross-react with tumor-associated antigens. We identified major histocompatibility complex …
Downregulation of microRNA-126 contributes to the failing right ventricle in pulmonary arterial hypertension
F Potus, G Ruffenach, A Dahou, C Thebault… - Circulation, 2015 - Am Heart Assoc
Background—Right ventricular (RV) failure is the most important factor of both morbidity and
mortality in pulmonary arterial hypertension (PAH). However, the underlying mechanisms …
mortality in pulmonary arterial hypertension (PAH). However, the underlying mechanisms …
Genome-wide association study of susceptibility to idiopathic pulmonary fibrosis
Rationale: Idiopathic pulmonary fibrosis (IPF) is a complex lung disease characterized by
scarring of the lung that is believed to result from an atypical response to injury of the …
scarring of the lung that is believed to result from an atypical response to injury of the …