The only licensed vaccine against tuberculosis (TB), bacille Calmette–Guérin (BCG),
protects against severe extrapulmonary forms of TB but is virtually ineffective against the …

Mumps epidemics in Canada and the United States prompted us to review evidence for the
effectiveness of 5 different vaccine strains. Early trials with the Jeryl Lynn vaccine strain …

Introduction COVID-19 vaccines have been highly effective in reducing morbidity and
mortality during the pandemic. While primary series vaccination rates are generally high in …

Background An effective, affordable, multivalent meningococcal conjugate vaccine is
needed to prevent epidemic meningitis in the African meningitis belt. Data on the safety and …

Background Group A meningococci are the source of major epidemics of meningitis in
Africa. An affordable, highly immunogenic meningococcal A conjugate vaccine is needed …

Rotavirus is the most common cause of moderate-to-severe infant diarrhoea in developing
countries, resulting in enormous morbidity, mortality, and economic burden. A bovine-human …

Background Tuberculosis is a major public health problem worldwide. Immunisation with
Mycobacterium bovis BCG vaccine is partially effective in infants, reducing the incidence of …

Introduction COVID-19 vaccines have been highly effective in reducing morbidity and
mortality during the pandemic. However, the emergence of the Omicron variant and …

Background Aerosolized vaccine can be used as a needle-free method of immunization
against measles, a disease that remains a major cause of illness and death. Data on the …

Background Invasive meningococcal disease is an important public health problem,
especially in sub-Saharan Africa. After introduction of MenAfriVac in 2010, Neisseria …