Expression profiling of microRNAs by deep sequencing
CJ Creighton, JG Reid… - Briefings in bioinformatics, 2009 - academic.oup.com
MicroRNAs are short non-coding RNAs that regulate the stability and translation of mRNAs.
Profiling experiments, using microarray or deep sequencing technology, have identified …
Profiling experiments, using microarray or deep sequencing technology, have identified …
Recent developments and therapeutic strategies against hepatocellular carcinoma
Hepatocellular carcinoma (HCC) has emerged as a major cause of cancer deaths globally.
The landscape of systemic therapy has recently changed, with six additional systemic …
The landscape of systemic therapy has recently changed, with six additional systemic …
[PDF][PDF] The somatic genomic landscape of chromophobe renal cell carcinoma
We describe the landscape of somatic genomic alterations of 66 chromophobe renal cell
carcinomas (ChRCCs) on the basis of multidimensional and comprehensive …
carcinomas (ChRCCs) on the basis of multidimensional and comprehensive …
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
DS Gerhard, L Wagner, EA Feingold… - Genome …, 2004 - europepmc.org
Abstract The National Institutes of Health's Mammalian Gene Collection (MGC) project was
designed to generate and sequence a publicly accessible cDNA resource containing a …
designed to generate and sequence a publicly accessible cDNA resource containing a …
[PDF][PDF] A comprehensive pan-cancer molecular study of gynecologic and breast cancers
We analyzed molecular data on 2,579 tumors from The Cancer Genome Atlas (TCGA) of
four gynecological types plus breast. Our aims were to identify shared and unique molecular …
four gynecological types plus breast. Our aims were to identify shared and unique molecular …
Embryonic stem cell microRNAs: defining factors in induced pluripotent (iPS) and cancer (CSC) stem cells?
PH Gunaratne - Current stem cell research & therapy, 2009 - ingentaconnect.com
The discovery of microRNAs (miRNAs-small non-coding RNAs of~ 22 nt) heralded a new
and exciting era in biology. During this period miRNAs have gone from ignominy due to their …
and exciting era in biology. During this period miRNAs have gone from ignominy due to their …
Deletion of Dicer in somatic cells of the female reproductive tract causes sterility
AK Nagaraja, C Andreu-Vieyra, HL Franco… - Molecular …, 2008 - academic.oup.com
Dicer is an evolutionarily conserved ribonuclease III that is necessary for microRNA (miRNA)
processing and the synthesis of small interfering RNAs from long double-stranded RNA …
processing and the synthesis of small interfering RNAs from long double-stranded RNA …
Molecular profiling uncovers a p53-associated role for microRNA-31 in inhibiting the proliferation of serous ovarian carcinomas and other cancers
MicroRNAs (miRNA) regulate complex patterns of gene expression, and the relevance of
altered miRNA expression to ovarian cancer remains to be elucidated. By comprehensively …
altered miRNA expression to ovarian cancer remains to be elucidated. By comprehensively …
A link between mir-100 and FRAP1/mTOR in clear cell ovarian cancer
MicroRNAs (miRNAs) are small noncoding RNAs that direct gene regulation through
translational repression and degradation of complementary mRNA. Although miRNAs have …
translational repression and degradation of complementary mRNA. Although miRNAs have …
Oncogenic lncRNA downregulates cancer cell antigen presentation and intrinsic tumor suppression
How tumor cells genetically lose antigenicity and evade immune checkpoints remains
largely elusive. We report that tissue-specific expression of the human long noncoding RNA …
largely elusive. We report that tissue-specific expression of the human long noncoding RNA …