Oxidative stress plays a dominant role in inflammatory skin diseases. Emerging evidence
has shown that the close interaction occurred between oxidative stress and the gut …

Autoimmune diseases are increasingly linked to aberrant gut microbiome and relevant
metabolites. However, the association between vitiligo and the gut microbiome remains to …

Vitiligo is an autoimmune skin disease resulting from epidermal melanocyte destruction
mediated by CD8+ T cells that breach the self-tolerance. Regulatory T cells (Tregs) are …

Vitiligo is a depigmentation disorder that develops as a result of the progressive
disappearance of epidermal melanocytes. The elevated level of amino acid metabolite …

Background The therapeutic effect of immune checkpoint blockers, especially the
neutralizing antibodies of programmed cell death (PD-1) and its ligand programmed death …

Vitiligo is a disfiguring disease featuring chemokines-mediated cutaneous infiltration of
autoreactive CD8+ T cells that kill melanocytes. Copious studies have indicated that virus …

Osteoporosis (OP) is a severe global health issue that has significant implications for
productivity and human lifespan. Gut microbiota dysbiosis has been demonstrated to be …

Vitiligo is a depigmented skin disorder caused by a variety of factors, including autoimmune,
metabolic disturbance or their combined effect, etc. Non-targeted metabolomic analyses …

Gastric cancer is the third most common cause of cancer-related deaths and is the fifth
highest incidence of cancer worldwide, especially in Eastern Asia, Central and Eastern …

Mesenchymal stem cells (MSCs) are promising vehicles for the delivery of anticancer agents
in cancer therapy. However, the tumor targeting of loaded therapeutics is essential. Here, we …