User profiles for "author:Sara Pai"
 | Sara PaiAssociate Professor, Harvard Medical School Verified email at mgh.harvard.edu Cited by 13221 |
Molecular pathology of head and neck cancer: implications for diagnosis, prognosis, and treatment
The prototypic head and neck squamous cell carcinoma (HNSCC) arises from the mucosal
lining of the upper aerodigestive tract, demonstrates squamous differentiation …
lining of the upper aerodigestive tract, demonstrates squamous differentiation …
Prospects of RNA interference therapy for cancer
RNA interference (RNAi) is a powerful gene-silencing process that holds great promise in
the field of cancer therapy. The discovery of RNAi has generated enthusiasm within the …
the field of cancer therapy. The discovery of RNAi has generated enthusiasm within the …
B7-DC, a new dendritic cell molecule with potent costimulatory properties for T cells
SY Tseng, M Otsuji, K Gorski, X Huang… - The Journal of …, 2001 - rupress.org
Dendritic cells (DCs), unique antigen-presenting cells (APCs) with potent T cell stimulatory
capacity, direct the activation and differentiation of T cells by providing costimulatory signals …
capacity, direct the activation and differentiation of T cells by providing costimulatory signals …
Association between BRAF V600E mutation and mortality in patients with papillary thyroid cancer
M Xing, AS Alzahrani, KA Carson, D Viola, R Elisei… - Jama, 2013 - jamanetwork.com
Importance BRAF V600E is a prominent oncogene in papillary thyroid cancer (PTC), but its
role in PTC-related patient mortality has not been established. Objective To investigate the …
role in PTC-related patient mortality has not been established. Objective To investigate the …
Evidence for a role of the PD-1: PD-L1 pathway in immune resistance of HPV-associated head and neck squamous cell carcinoma
Human papillomavirus-associated head and neck squamous cell carcinomas (HPV-
HNSCC) originate in the tonsils, the major lymphoid organ that orchestrates immunity to oral …
HNSCC) originate in the tonsils, the major lymphoid organ that orchestrates immunity to oral …
PET/CT in the management of thyroid cancers
C Marcus, PW Whitworth, DS Surasi… - American Journal of …, 2014 - Am Roentgen Ray Soc
OBJECTIVE. Thyroid cancer is the most common endocrine cancer. This review evaluates
the established use of 18F-FDG PET/CT in papillary, follicular, Hürthle cell, anaplastic, and …
the established use of 18F-FDG PET/CT in papillary, follicular, Hürthle cell, anaplastic, and …
[PDF][PDF] Successful anti-PD-1 cancer immunotherapy requires T cell-dendritic cell crosstalk involving the cytokines IFN-γ and IL-12
Anti-PD-1 immune checkpoint blockers can induce sustained clinical responses in cancer
but how they function in vivo remains incompletely understood. Here, we combined intravital …
but how they function in vivo remains incompletely understood. Here, we combined intravital …
[HTML][HTML] BRAF V600E and TERT promoter mutations cooperatively identify the most aggressive papillary thyroid cancer with highest recurrence
BRAF V600E and TERT Promoter Mutations Cooperatively Identify the Most Aggressive
Papillary Thyroid Cancer With Highest Recurrence - PMC Back to Top Skip to main content NIH …
Papillary Thyroid Cancer With Highest Recurrence - PMC Back to Top Skip to main content NIH …
[HTML][HTML] Highly prevalent TERT promoter mutations in aggressive thyroid cancers
Abstract Mutations 1 295 228 C> T and 1 295 250 C> T (termed C228T and C250T
respectively), corresponding to− 124 C> T and− 146 C> T from the translation start site in the …
respectively), corresponding to− 124 C> T and− 146 C> T from the translation start site in the …
Cystic lymph node metastasis in patients with head and neck cancer: an HPV‐associated phenomenon
Background. Cystic lymph node metastases have been associated with tonsil cancer. A
subset of oropharyngeal cancers contain human papillomavirus (HPV) DNA. The clinical …
subset of oropharyngeal cancers contain human papillomavirus (HPV) DNA. The clinical …