While colorectal cancers (CRC) are paradigmatic tumors invaded by effector memory
lymphocytes, the mechanisms accounting for the relative resistance of MSI negative CRC to …

Abstract Treatment with combined immune checkpoint blockade (CICB) targeting CTLA-4
and PD-1 is associated with clinical benefit across tumor types, but also a high rate of …

Antibiotics (ABX) compromise the efficacy of programmed cell death protein 1 (PD-1)
blockade in cancer patients, but the mechanisms underlying their immunosuppressive …

The prognosis of colon cancer (CC) is dictated by tumor-infiltrating lymphocytes, including
follicular helper T (TFH) cells and the efficacy of chemotherapy-induced immune responses …

Gut dysbiosis has been associated with intestinal and extraintestinal malignancies, but
whether and how carcinogenesis drives compositional shifts of the microbiome to its own …

Context Body mass index (BMI) is a useful tool for measuring body composition. It is unclear
whether high BMI is a favourable indicator in patients with metastatic renal cell carcinoma …

Sarcoidosis is a disease of unknown etiology in which granulomas form throughout the body
and is typically treated with glucocorticoids, but there are no approved steroid-sparing …

Background Prostate cancer (PC) responds to androgen deprivation therapy (ADT) usually
in a transient fashion, progressing from hormone-sensitive PC (HSPC) to castration-resistant …

Background: Dental caries (DC) are more prevalent in individuals with diabetes than in
healthy individuals. However, the association between glycaemic control and DC has not …

A deviated repertoire of the gut microbiome predicts resistance to cancer immunotherapy.
Enterococcus hirae compensated cancer-associated dysbiosis in various tumor models …