Background Uveal melanoma is a disease that is distinct from cutaneous melanoma, with a
low tumor mutational burden and a 1-year overall survival of approximately 50% in patients …

Patients with Philadelphia chromosome-negative myeloproliferative neoplasms (MPN) like
polycythemia vera and essential thrombocythemia are at increased risk of arterial and …

Relapse remains a leading cause of death after allogeneic hematopoietic cell
transplantation (HCT) for patients with high-risk leukemias. The potentially beneficial donor …

Background Tebentafusp, a T-cell receptor–bispecific molecule that targets glycoprotein 100
and CD3, is approved for adult patients who are positive for HLA-A* 02: 01 and have …

Background Results from a phase 2 trial of the TPEx chemotherapy regimen (docetaxel–
platinum–cetuximab) showed promising results, with a median overall survival of 14· 0 …

Summary Background Phosphatidylinositol 3-kinase (PI3K) pathway activation in squamous
cell carcinoma of the head and neck contributes to treatment resistance and disease …

Systemic pan-tumor analyses may reveal the significance of common features implicated in
cancer immunogenicity and patient survival. Here, we provide a comprehensive multi-omics …

Multilocus enzyme electrophoresis (MLEE) is the gold standard for taxonomy and strain
typing of Leishmania, but has some limitations. An alternative reliable and fast genotyping …

The Leishmania donovani complex, which consists of L. donovani, L. infantum-L. chagasi,
and L. archibaldi, is responsible for visceral manifestations of leishmaniasis. Multilocus …

Background Leishmania infantum is the causative agent of visceral and cutaneous
leishmaniasis in the Mediterranean region, South America, and China. MON-1 L. infantum is …