User profiles for "author:Seongyeol Park"
Seongyeol ParkKorea Advanced Institute of Science and Technology Verified email at kaist.ac.kr Cited by 1579 |
[PDF][PDF] Clonal history and genetic predictors of transformation into small-cell carcinomas from lung adenocarcinomas
Purpose Histologic transformation of EGFR mutant lung adenocarcinoma (LADC) into small-
cell lung cancer (SCLC) has been described as one of the major resistant mechanisms for …
cell lung cancer (SCLC) has been described as one of the major resistant mechanisms for …
Association between expression level of PD1 by tumor-infiltrating CD8+ T cells and features of hepatocellular carcinoma
Background & Aims T-cell exhaustion, or an impaired capacity to secrete cytokines and
proliferate with overexpression of immune checkpoint receptors, occurs during chronic viral …
proliferate with overexpression of immune checkpoint receptors, occurs during chronic viral …
[PDF][PDF] Tracing oncogene rearrangements in the mutational history of lung adenocarcinoma
Mutational processes giving rise to lung adenocarcinomas (LADCs) in non-smokers remain
elusive. We analyzed 138 LADC whole genomes, including 83 cases with minimal …
elusive. We analyzed 138 LADC whole genomes, including 83 cases with minimal …
Clonal dynamics in early human embryogenesis inferred from somatic mutation
Cellular dynamics and fate decision in early human embryogenesis remain largely unknown
owing to the challenges of performing studies in human embryos. Here, we explored whole …
owing to the challenges of performing studies in human embryos. Here, we explored whole …
[HTML][HTML] Serotonin signals through a gut-liver axis to regulate hepatic steatosis
Nonalcoholic fatty liver disease (NAFLD) is increasing in worldwide prevalence, closely
tracking the obesity epidemic, but specific pharmaceutical treatments for NAFLD are lacking …
tracking the obesity epidemic, but specific pharmaceutical treatments for NAFLD are lacking …
[PDF][PDF] 4‐1BB Delineates Distinct Activation Status of Exhausted Tumor‐Infiltrating CD8+ T Cells in Hepatocellular Carcinoma
Background and Aims Targeting costimulatory receptors with agonistic antibodies is a
promising cancer immunotherapy option. We aimed to investigate costimulatory receptor …
promising cancer immunotherapy option. We aimed to investigate costimulatory receptor …
Mutalisk: a web-based somatic MUTation AnaLyIS toolKit for genomic, transcriptional and epigenomic signatures
Somatic genome mutations occur due to combinations of various intrinsic/extrinsic
mutational processes and DNA repair mechanisms. Different molecular processes …
mutational processes and DNA repair mechanisms. Different molecular processes …
[HTML][HTML] 4-1BB co-stimulation further enhances anti-PD-1-mediated reinvigoration of exhausted CD39+ CD8 T cells from primary and metastatic sites of epithelial …
G Leem, J Park, M Jeon, ES Kim, SW Kim… - … for immunotherapy of …, 2020 - ncbi.nlm.nih.gov
Background Responses to immunotherapy vary between different cancer types and sites.
Here, we aimed to investigate features of exhaustion and activation in tumor-infiltrating CD8 …
Here, we aimed to investigate features of exhaustion and activation in tumor-infiltrating CD8 …
Advancements of remote data acquisition and processing in unmanned vehicle technologies for water quality monitoring: An extensive review
Regular water quality monitoring is becoming desirable due to the increase in water
pollution caused by both climate change and the generation of industrial chemicals …
pollution caused by both climate change and the generation of industrial chemicals …
MET amplification, protein expression, and mutations in pulmonary adenocarcinoma
Objectives MET amplification, protein expression, and splice mutations at exon 14 are
known to cause dysregulation of the MET/HGF pathway. Our study aimed to confirm the …
known to cause dysregulation of the MET/HGF pathway. Our study aimed to confirm the …