[HTML][HTML] Long non-coding RNA MEG3 promotes cisplatin-induced nephrotoxicity through regulating AKT/TSC/mTOR-mediated autophagy
Abstract Cis-Diamminedichloroplatinum (II)(DDP)-induced nephrotoxicity (DDPIN) may
cause irreversible renal injury associated with high morbidity and mortality. Current standard …
cause irreversible renal injury associated with high morbidity and mortality. Current standard …
[HTML][HTML] Local transmission and global dissemination of New Delhi Metallo-Beta-Lactamase (NDM): a whole genome analysis
Abstract Background New Delhi metallo-β-lactamase (bla NDM), a plasmid-borne
carbapenemase gene associated with significant mortality and severely limited treatment …
carbapenemase gene associated with significant mortality and severely limited treatment …
Competing engagement of β-arrestin isoforms balances IGF1R/p53 signaling and controls melanoma cell chemotherapeutic responsiveness
Constraints on the p53 tumor suppressor pathway have long been associated with the
progression, therapeutic resistance, and poor prognosis of melanoma, the most aggressive …
progression, therapeutic resistance, and poor prognosis of melanoma, the most aggressive …
[HTML][HTML] GABPA-activated TGFBR2 transcription inhibits aggressiveness but is epigenetically erased by oncometabolites in renal cell carcinoma
Background The ETS transcription factor GABPA has long been thought of as an oncogenic
factor and recently suggested as a target for cancer therapy due to its critical effect on …
factor and recently suggested as a target for cancer therapy due to its critical effect on …
[HTML][HTML] A2B adenosine receptor antagonists rescue lymphocyte activity in adenosine-producing patient-derived cancer models
Background Adenosine is a metabolite that suppresses antitumor immune response of T
and NK cells via extracellular binding to the two subtypes of adenosine-2 receptors, A 2 …
and NK cells via extracellular binding to the two subtypes of adenosine-2 receptors, A 2 …
[BOOK][B] Uniquely Nk Cells: The Multifaceted Roles of the Natural Killers
S Neo - 2021 - search.proquest.com
Natural killer cells (NK cells) were primarily discovered through the study of tumor cell
recognition during immune surveillance. Till date, many studies had characterized NK cells …
recognition during immune surveillance. Till date, many studies had characterized NK cells …
986 Distinct macrophage metabolism and phenotypic changes in viral and non-alcoholic fatty liver disease (NAFLD) related hepatocellular carcinoma
J Zhao, NEO Shiyong, SV Seow, TWH Shuen… - 2023 - jitc.bmj.com
Background Different aetiologies of hepatocellular carcinoma (HCC) may influence the
tumour microenvironment with implications for immunotherapy. Macrophages, especially the …
tumour microenvironment with implications for immunotherapy. Macrophages, especially the …
939 Unique profile of memory-derived regulatory B cells in viral-driven hepatocellular carcinoma
S Neo, KP Lam - 2023 - jitc.bmj.com
Background The functional plasticity of tumor-infiltrating B (TIL-B) cells spans from an array
of anti-tumor responses to non-canonical immune suppression but yet, its influence on the …
of anti-tumor responses to non-canonical immune suppression but yet, its influence on the …
Local transmission and global dissemination of New Delhi metallo-beta-lactamase (NDM): a whole genome analysis.
KWX Khong WeiXin, XEY Xia ErYu, K Marimuthu… - 2016 - cabidigitallibrary.org
Abstract Background: New Delhi metallo-β-lactamase (blaNDM), a plasmid-borne
carbapenemase gene associated with significant mortality and severely limited treatment …
carbapenemase gene associated with significant mortality and severely limited treatment …