Background Deciphering the correlation between immune-related adverse events (irAEs)
categorized by organ system class and clinical benefit of immunotherapy is critical for …

Purpose Vascular endothelial growth factor signaling pathway plays a crucial role in
angiogenesis and has become a promising target for cancer drug development. We aimed …

The discovery that mutations in the EGFR gene are present in up to 50% of patients with
lung adenocarcinoma, and the development of highly efficacious EGFR tyrosine kinase …

The treatment of myocardial infarction (MI) remains a substantial challenge due to excessive
inflammation, massive cell death, and restricted regenerative potential, leading to …

Background The third-generation epidermal growth factor receptor (EGFR)–tyrosine kinase
inhibitor (TKI) osimertinib has become the standard treatment for patients with pretreated …

Background Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) have
improved the prognosis of mutant lung cancer; however, the clinical application value of …

Background Transformation to small cell lung cancer (SCLC) is a resistance mechanism of
epidermal growth factor receptor (EGFR) mutant lung adenocarcinoma (LADC) patients …

Remarkable Li-ion battery (LIB) anode materials need to have long cycle life and fast
charge/discharge rate, however they are difficult to be realized in the monolayer anode …

Background The efficacy of crizotinib for anaplastic lymphoma kinase (ALK)-rearranged non-
small-cell lung cancer (NSCLC) patients with brain metastasis is controversial. Real-world …

Although the use of bioabsorbable occluder is expected to reduce the risk of metal occluder-
related complications, it has not been approved due to incomplete degradation and new …