Gelatin as a delivery vehicle for the controlled release of bioactive molecules
Gelatin is a commonly used natural polymer which is derived from collagen. The isoelectric
point of gelatin can be modified during the fabrication process to yield either a negatively …
point of gelatin can be modified during the fabrication process to yield either a negatively …
[PDF][PDF] How to increase serotonin in the human brain without drugs
SN Young - Journal of psychiatry & neuroscience: JPN, 2007 - jpn.ca
For the last 4 decades, the question of how to manipulate the serotonergic system with drugs
has been an important area of research in biological psychiatry, and this research has led to …
has been an important area of research in biological psychiatry, and this research has led to …
The role of serotonin in human mood and social interaction: insight from altered tryptophan levels
Alterations in brain tryptophan levels cause changes in brain serotonin synthesis, and this
has been used to study the implication of altered serotonin levels in humans. In the acute …
has been used to study the implication of altered serotonin levels in humans. In the acute …
Tryptophan depletion causes a rapid lowering of mood in normal males
SN Young, SE Smith, RO Pihl, FR Ervin - Psychopharmacology, 1985 - Springer
Normal male human subjects ingested amino acid mixtures which were tryptophan-free,
balanced or contained excess tryptophan. The tryptophan-free mixture causes a marked …
balanced or contained excess tryptophan. The tryptophan-free mixture causes a marked …
Dual delivery of an angiogenic and an osteogenic growth factor for bone regeneration in a critical size defect model
This study investigated the effects of dual delivery of vascular endothelial growth factor
(VEGF) and bone morphogenetic protein-2 (BMP-2) for bone regeneration in a rat cranial …
(VEGF) and bone morphogenetic protein-2 (BMP-2) for bone regeneration in a rat cranial …
Evaluation of bone regeneration using the rat critical size calvarial defect
PP Spicer, JD Kretlow, S Young, JA Jansen… - Nature protocols, 2012 - nature.com
Animal models that are reliably reproducible, appropriate analogs to the clinical condition
they are used to investigate, and that offer minimal morbidity and periprocedural mortality to …
they are used to investigate, and that offer minimal morbidity and periprocedural mortality to …
Ecological momentary assessment: what it is and why it is a method of the future in clinical psychopharmacology
DS Moskowitz, SN Young - Journal of Psychiatry and Neuroscience, 2006 - jpn.ca
Current methods of assessment in clinical psychopharmacology have several serious
disadvantages, particularly for the study of social functioning. We aimed to review the …
disadvantages, particularly for the study of social functioning. We aimed to review the …
Mood-lowering effect of tryptophan depletion: enhanced susceptibility in young men at genetic risk for major affective disorders
C Benkelfat, MA Ellenbogen, P Dean… - Archives of general …, 1994 - jamanetwork.com
Methods: A double-blind placebo-controlled cross-over study in which plasma tryptophan
was manipulated by administration of a tryptophan-deficient amino acid mixture. In the …
was manipulated by administration of a tryptophan-deficient amino acid mixture. In the …
Lipoic acid as a novel treatment for Alzheimer's disease and related dementias
L Holmquist, G Stuchbury, K Berbaum, S Muscat… - Pharmacology & …, 2007 - Elsevier
Alzheimer's disease (AD) is a progressive neurodegenerative disorder that destroys patient
memory and cognition, communication ability with the social environment and the ability to …
memory and cognition, communication ability with the social environment and the ability to …
[PDF][PDF] Trypanosoma brucei parasites occupy and functionally adapt to the adipose tissue in mice
S Trindade, F Rijo-Ferreira, T Carvalho… - Cell host & …, 2016 - cell.com
Trypanosoma brucei is an extracellular parasite that causes sleeping sickness. In
mammalian hosts, trypanosomes are thought to exist in two major niches: early in infection …
mammalian hosts, trypanosomes are thought to exist in two major niches: early in infection …