User profiles for "author:Simon Young"

Simon N Young

- Verified email at mcgill.ca - Cited by 19674

Simon Young

- Verified email at uth.tmc.edu - Cited by 5588

Simon A Young

- Verified email at st-andrews.ac.uk - Cited by 2848

Gelatin as a delivery vehicle for the controlled release of bioactive molecules

S Young, M Wong, Y Tabata, AG Mikos - Journal of controlled release, 2005 - Elsevier
Gelatin is a commonly used natural polymer which is derived from collagen. The isoelectric
point of gelatin can be modified during the fabrication process to yield either a negatively …

[PDF][PDF] How to increase serotonin in the human brain without drugs

SN Young - Journal of psychiatry & neuroscience: JPN, 2007 - jpn.ca
For the last 4 decades, the question of how to manipulate the serotonergic system with drugs
has been an important area of research in biological psychiatry, and this research has led to …

The role of serotonin in human mood and social interaction: insight from altered tryptophan levels

SN Young, M Leyton - Pharmacology Biochemistry and Behavior, 2002 - Elsevier
Alterations in brain tryptophan levels cause changes in brain serotonin synthesis, and this
has been used to study the implication of altered serotonin levels in humans. In the acute …

Tryptophan depletion causes a rapid lowering of mood in normal males

SN Young, SE Smith, RO Pihl, FR Ervin - Psychopharmacology, 1985 - Springer
Normal male human subjects ingested amino acid mixtures which were tryptophan-free,
balanced or contained excess tryptophan. The tryptophan-free mixture causes a marked …

Dual delivery of an angiogenic and an osteogenic growth factor for bone regeneration in a critical size defect model

ZS Patel, S Young, Y Tabata, JA Jansen, MEK Wong… - Bone, 2008 - Elsevier
This study investigated the effects of dual delivery of vascular endothelial growth factor
(VEGF) and bone morphogenetic protein-2 (BMP-2) for bone regeneration in a rat cranial …

Evaluation of bone regeneration using the rat critical size calvarial defect

PP Spicer, JD Kretlow, S Young, JA Jansen… - Nature protocols, 2012 - nature.com
Animal models that are reliably reproducible, appropriate analogs to the clinical condition
they are used to investigate, and that offer minimal morbidity and periprocedural mortality to …

Ecological momentary assessment: what it is and why it is a method of the future in clinical psychopharmacology

DS Moskowitz, SN Young - Journal of Psychiatry and Neuroscience, 2006 - jpn.ca
Current methods of assessment in clinical psychopharmacology have several serious
disadvantages, particularly for the study of social functioning. We aimed to review the …

Mood-lowering effect of tryptophan depletion: enhanced susceptibility in young men at genetic risk for major affective disorders

C Benkelfat, MA Ellenbogen, P Dean… - Archives of general …, 1994 - jamanetwork.com
Methods: A double-blind placebo-controlled cross-over study in which plasma tryptophan
was manipulated by administration of a tryptophan-deficient amino acid mixture. In the …

Lipoic acid as a novel treatment for Alzheimer's disease and related dementias

L Holmquist, G Stuchbury, K Berbaum, S Muscat… - Pharmacology & …, 2007 - Elsevier
Alzheimer's disease (AD) is a progressive neurodegenerative disorder that destroys patient
memory and cognition, communication ability with the social environment and the ability to …

[PDF][PDF] Trypanosoma brucei parasites occupy and functionally adapt to the adipose tissue in mice

S Trindade, F Rijo-Ferreira, T Carvalho… - Cell host & …, 2016 - cell.com
Trypanosoma brucei is an extracellular parasite that causes sleeping sickness. In
mammalian hosts, trypanosomes are thought to exist in two major niches: early in infection …