User profiles for "author:Ssu-Hsueh Tseng"
 | Ssu-Hsueh TsengJohns Hopkins University Verified email at jhmi.edu Cited by 333 |
[HTML][HTML] In situ vaccination via tissue-targeted cDC1 expansion enhances the immunogenicity of chemoradiation and immunotherapy
Even with the prolific clinical use of next-generation cancer therapeutics, many tumors
remain unresponsive or become refractory to therapy, creating a medical need. In cancer …
remain unresponsive or become refractory to therapy, creating a medical need. In cancer …
Protein detection in blood with single-molecule imaging
The ability to characterize individual biomarker protein molecules in patient blood samples
could enable diagnosis of diseases at an earlier stage, when treatment is typically more …
could enable diagnosis of diseases at an earlier stage, when treatment is typically more …
[HTML][HTML] Bioinformatics and in vitro experimental analyses identify the selective therapeutic potential of interferon gamma and apigenin against cervical squamous cell …
The clinical management and treatment of cervical cancer, one of the most commonly
diagnosed cancers and a leading cause of cancer-related female death, remains a huge …
diagnosed cancers and a leading cause of cancer-related female death, remains a huge …
[HTML][HTML] A novel pseudovirus‐based mouse model of SARS-CoV-2 infection to test COVID-19 interventions
SH Tseng, B Lam, YJ Kung, J Lin, L Liu, YC Tsai… - Journal of biomedical …, 2021 - Springer
Background The spread of SARS-CoV-2, the virus that causes Coronavirus Disease 2019
(COVID-19), has been characterized as a worldwide pandemic. Currently, there are few …
(COVID-19), has been characterized as a worldwide pandemic. Currently, there are few …
K14‐EGFP‐miR‐31 transgenic mice have high susceptibility to chemical‐induced squamous cell tumorigenesis that is associating with Ku80 repression
Squamous cell carcinoma (SCC) occurring in the head and neck region and the esophagus
causes tremendous cancer mortality around the world. miR‐31 is among the most eminently …
causes tremendous cancer mortality around the world. miR‐31 is among the most eminently …
[HTML][HTML] Up-regulation of miR-187 modulates the advances of oral carcinoma by targeting BARX2 tumor suppressor
Oral squamous cell carcinoma (OSCC) is one of the most common cancers worldwide.
Aberrations in miRNA regulation are known to play important roles in OSCC pathogenesis …
Aberrations in miRNA regulation are known to play important roles in OSCC pathogenesis …
[HTML][HTML] TLR9 acts as a sensor for tumor-released DNA to modulate anti-tumor immunity after chemotherapy
TH Kang, CP Mao, YS Kim, TW Kim, A Yang… - … for immunotherapy of …, 2019 - Springer
The tumor microenvironment exists in a state of dynamic equilibrium, in which a balance of
agonist and antagonist signals govern the anti-tumor immune responses. Previous studies …
agonist and antagonist signals govern the anti-tumor immune responses. Previous studies …
[HTML][HTML] Localization of Salmonella and albumin-IL-2 to the tumor microenvironment augments anticancer T cell immunity
YJ Kung, B Lam, SH Tseng, A MacDonald… - Journal of biomedical …, 2022 - Springer
Background For centuries, microbial-based agents have been investigated as a therapeutic
modality for the treatment of cancer. In theory, these methods would be cheap to produce …
modality for the treatment of cancer. In theory, these methods would be cheap to produce …
Development of a novel mouse model of spontaneous high-risk HPVE6/E7–expressing carcinoma in the cervicovaginal tract
Current preclinical models for cervical cancer lack important clinical and pathologic features.
To improve upon these models, we aimed to develop a novel, spontaneous HPV16 …
To improve upon these models, we aimed to develop a novel, spontaneous HPV16 …
[HTML][HTML] RPN13/ADRM1 inhibitor reverses immunosuppression by myeloid-derived suppressor cells
Myeloid-derived-suppressor cells (MDSCs) are key mediators of immune suppression in the
ovarian tumor microenvironment. Modulation of MDSC function to relieve …
ovarian tumor microenvironment. Modulation of MDSC function to relieve …