Pathological response after neoadjuvant chemotherapy in resectable non-small-cell lung cancers: proposal for the use of major pathological response as a surrogate …

MD Hellmann, JE Chaft, WN William, V Rusch… - The lancet …, 2014 - thelancet.com
Improvements in outcomes for patients with resectable lung cancers have plateaued.
Clinical trials of resectable non-small-cell lung cancers with overall survival as the primary …

Worldwide esophageal cancer collaboration

TW Rice, VW Rusch… - Diseases of the …, 2009 - academic.oup.com
The aim of this study is to report assemblage of a large multi-institutional international
database of esophageal cancer patients, patient and tumor characteristics, and survival of …

Utility of PET, CT, and EUS to identify pathologic responders in esophageal cancer

SG Swisher, M Maish, JJ Erasmus, AM Correa… - The Annals of thoracic …, 2004 - Elsevier
BACKGROUND: This study evaluates the utility of positron emission tomography (PET),
endoscopic ultrasonography (EUS), and computed tomographic (CT) scans to predict …

Local consolidative therapy versus maintenance therapy or observation for patients with oligometastatic non-small-cell lung cancer without progression after first-line …

DR Gomez, GR Blumenschein, JJ Lee… - The lancet …, 2016 - thelancet.com
Background Evidence from retrospective studies suggests that disease progression after first-
line chemotherapy for metastatic non-small-cell lung cancer (NSCLC) occurs most often at …

[HTML][HTML] Local consolidative therapy vs. maintenance therapy or observation for patients with oligometastatic non–small-cell lung cancer: long-term results of a multi …

DR Gomez, C Tang, J Zhang… - Journal of Clinical …, 2019 - ncbi.nlm.nih.gov
PURPOSE Our previously published findings reported that local consolidative therapy (LCT)
with radiotherapy or surgery improved progression-free survival (PFS) and delayed new …

Neoadjuvant nivolumab or nivolumab plus ipilimumab in operable non-small cell lung cancer: the phase 2 randomized NEOSTAR trial

T Cascone, WN William Jr, A Weissferdt, CH Leung… - Nature medicine, 2021 - nature.com
Ipilimumab improves clinical outcomes when combined with nivolumab in metastatic non-
small cell lung cancer (NSCLC), but its efficacy and impact on the immune …

[HTML][HTML] Neoadjuvant chemotherapy plus nivolumab with or without ipilimumab in operable non-small cell lung cancer: the phase 2 platform NEOSTAR trial

T Cascone, CH Leung, A Weissferdt, A Pataer… - Nature medicine, 2023 - nature.com
Abstract Neoadjuvant ipilimumab+ nivolumab (Ipi+ Nivo) and nivolumab+ chemotherapy
(Nivo+ CT) induce greater pathologic response rates than CT alone in patients with …

Adenovirus-mediated p53 gene transfer in advanced non-small-cell lung cancer

SG Swisher, JA Roth, J Nemunaitis… - Journal of the …, 1999 - academic.oup.com
BACKGROUND: Preclinical studies in animal models have demonstrated tumor regression
following intratumoral administration of an adenovirus vector containing wild-type p53 …

Transthoracic vertebrectomy for metastatic spinal tumors

ZL Gokaslan, JE York, GL Walsh, IE McCutcheon… - Journal of …, 1998 - thejns.org
Object. Anterior approaches to the spine for the treatment of spinal tumors have gained
acceptance; however, in most published reports, patients with primary, metastatic, or chest …

[PDF][PDF] Patterns of transcription factor programs and immune pathway activation define four major subtypes of SCLC with distinct therapeutic vulnerabilities

CM Gay, CA Stewart, EM Park, L Diao, SM Groves… - Cancer cell, 2021 - cell.com
Despite molecular and clinical heterogeneity, small cell lung cancer (SCLC) is treated as a
single entity with predictably poor results. Using tumor expression data and non-negative …