Objective Gastric cancer is a major gastrointestinal malignancy for which targeted therapies
are emerging as treatment options. This study sought to identify the most prevalent …

Background Lenvatinib in combination with pembrolizumab or everolimus has activity
against advanced renal cell carcinoma. The efficacy of these regimens as compared with …

Bevacizumab in Combination With Chemotherapy As First-Line Therapy in Advanced Gastric
Cancer: A Randomized, Double-Blind, Place Page 1 Bevacizumab in Combination With …

Abstract Background KRAS p. G12C mutation occurs in approximately 1 to 2% of pancreatic
cancers. The safety and efficacy of sotorasib, a KRAS G12C inhibitor, in previously treated …

Summary Background The International Metastatic Renal-Cell Carcinoma Database
Consortium model offers prognostic information for patients with metastatic renal-cell …

Gastric cancer is a major cause of global cancer mortality. We surveyed the spectrum of
somatic alterations in gastric cancer by sequencing the exomes of 15 gastric …

Genexol-PM is a novel Cremophor EL-free polymeric micelle formulation of paclitaxel. This
single arm, multicenter phase II study was designed to evaluate the efficacy and safety of …

Background A non-randomised, phase 2 study showed activity and tolerability of eribulin in
advanced or metastatic soft-tissue sarcoma. In this phase 3 study, we aimed to compare …

PURPOSE Adjuvant chemotherapy after D2 gastrectomy is standard for resectable locally
advanced gastric cancer (LAGC) in Asia. Based on positive findings for perioperative …

Background The benefit of cytoreductive nephrectomy (CN) for overall survival (OS) is
unclear in patients with synchronous metastatic renal cell carcinoma (mRCC) in the era of …