The microbiome in allergic disease: current understanding and future opportunities—2017 PRACTALL document of the American Academy of Allergy, Asthma & …

YJ Huang, BJ Marsland, S Bunyavanich… - Journal of Allergy and …, 2017 - Elsevier
PRACTALL is a joint initiative of the American Academy of Allergy, Asthma & Immunology
and the European Academy of Allergy and Clinical Immunology to provide shared evidence …

Epinephrine for first-aid management of anaphylaxis

SH Sicherer, F Simons, TA Mahr, SL Abramson… - …, 2017 - publications.aap.org
Epinephrine for First-aid Management of Anaphylaxis | Pediatrics | American Academy of
Pediatrics Skip to Main Content Disclaimer » Advertising AAP logo Search Close Shopping …

Recommendations for live viral and bacterial vaccines in immunodeficient patients and their close contacts

MAC of the Immune, WT Shearer, TA Fleisher… - Journal of allergy and …, 2014 - Elsevier
The present uncertainty of which live viral or bacterial vaccines can be given to
immunodeficient patients and the growing neglect of societal adherence to routine …

[HTML][HTML] Activated STING in a vascular and pulmonary syndrome

Y Liu, AA Jesus, B Marrero, D Yang… - … England Journal of …, 2014 - Mass Medical Soc
Background The study of autoinflammatory diseases has uncovered mechanisms
underlying cytokine dysregulation and inflammation. Methods We analyzed the DNA of an …

[HTML][HTML] Age, thymopoiesis, and CD4+ T-lymphocyte regeneration after intensive chemotherapy

CL Mackall, TA Fleisher, MR Brown… - … England Journal of …, 1995 - Mass Medical Soc
Background Inadequate reconstitution of CD4+ T lymphocytes is an important clinical
problem complicating chemotherapy, human immunodeficiency virus infection, and bone …

[HTML][HTML] Redistribution, hyperproliferation, activation of natural killer cells and CD8 T cells, and cytokine production during first-in-human clinical trial of recombinant …

KC Conlon, E Lugli, HC Welles… - Journal of clinical …, 2015 - ncbi.nlm.nih.gov
Purpose Interleukin-15 (IL-15) has significant potential in cancer immunotherapy as an
activator of antitumor CD8 T and natural killer (NK) cells. The primary objectives of this trial …

[HTML][HTML] Early-onset stroke and vasculopathy associated with mutations in ADA2

Q Zhou, D Yang, AK Ombrello… - … England Journal of …, 2014 - Mass Medical Soc
Background We observed a syndrome of intermittent fevers, early-onset lacunar strokes and
other neurovascular manifestations, livedoid rash, hepatosplenomegaly, and systemic …

Immune dysregulation in human subjects with heterozygous germline mutations in CTLA4

HS Kuehn, W Ouyang, B Lo, EK Deenick, JE Niemela… - Science, 2014 - science.org
Cytotoxic T lymphocyte antigen–4 (CTLA-4) is an inhibitory receptor found on immune cells.
The consequences of mutations in CTLA4 in humans are unknown. We identified germline …

Dominant-activating germline mutations in the gene encoding the PI (3) K catalytic subunit p110δ result in T cell senescence and human immunodeficiency

CL Lucas, HS Kuehn, F Zhao, JE Niemela… - Nature …, 2014 - nature.com
The p110δ subunit of phosphatidylinositol-3-OH kinase (PI (3) K) is selectively expressed in
leukocytes and is critical for lymphocyte biology. Here we report fourteen patients from …

[HTML][HTML] Transplantation outcomes for severe combined immunodeficiency, 2000–2009

SY Pai, BR Logan, LM Griffith… - … England Journal of …, 2014 - Mass Medical Soc
Background The Primary Immune Deficiency Treatment Consortium was formed to analyze
the results of hematopoietic-cell transplantation in children with severe combined …