[PDF][PDF] Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis
HS Phillips, S Kharbanda, R Chen, WF Forrest… - Cancer cell, 2006 - cell.com
Previously undescribed prognostic subclasses of high-grade astrocytoma are identified and
discovered to resemble stages in neurogenesis. One tumor class displaying neuronal …
discovered to resemble stages in neurogenesis. One tumor class displaying neuronal …
GMAP: a genomic mapping and alignment program for mRNA and EST sequences
TD Wu, CK Watanabe - Bioinformatics, 2005 - academic.oup.com
Motivation: We introduce gmap, a standalone program for mapping and aligning cDNA
sequences to a genome. The program maps and aligns a single sequence with minimal …
sequences to a genome. The program maps and aligns a single sequence with minimal …
Fast and SNP-tolerant detection of complex variants and splicing in short reads
TD Wu, S Nacu - Bioinformatics, 2010 - academic.oup.com
Motivation: Next-generation sequencing captures sequence differences in reads relative to a
reference genome or transcriptome, including splicing events and complex variants …
reference genome or transcriptome, including splicing events and complex variants …
Comprehensive genomic analysis identifies SOX2 as a frequently amplified gene in small-cell lung cancer
CM Rudin, S Durinck, EW Stawiski, JT Poirier… - Nature …, 2012 - nature.com
Small-cell lung cancer (SCLC) is an exceptionally aggressive disease with poor prognosis.
Here, we obtained exome, transcriptome and copy-number alteration data from …
Here, we obtained exome, transcriptome and copy-number alteration data from …
[HTML][HTML] Recurrent R-spondin fusions in colon cancer
S Seshagiri, EW Stawiski, S Durinck, Z Modrusan… - Nature, 2012 - nature.com
Identifying and understanding changes in cancer genomes is essential for the development
of targeted therapeutics. Here we analyse systematically more than 70 pairs of primary …
of targeted therapeutics. Here we analyse systematically more than 70 pairs of primary …
Comprehensive genomic analysis of malignant pleural mesothelioma identifies recurrent mutations, gene fusions and splicing alterations
R Bueno, EW Stawiski, LD Goldstein, S Durinck… - Nature …, 2016 - nature.com
Abstract We analyzed transcriptomes (n= 211), whole exomes (n= 99) and targeted exomes
(n= 103) from 216 malignant pleural mesothelioma (MPM) tumors. Using RNA-seq data, we …
(n= 103) from 216 malignant pleural mesothelioma (MPM) tumors. Using RNA-seq data, we …
[PDF][PDF] The Secure Remote Password Protocol.
TD Wu - NDSS, 1998 - Citeseer
This paper presents a new password authentication and key-exchange protocol suitable for
authenticating users and exchanging keys over an untrusted network. The new protocol …
authenticating users and exchanging keys over an untrusted network. The new protocol …
A comprehensive transcriptional portrait of human cancer cell lines
C Klijn, S Durinck, EW Stawiski, PM Haverty… - Nature …, 2015 - nature.com
Tumor-derived cell lines have served as vital models to advance our understanding of
oncogene function and therapeutic responses. Although substantial effort has been made to …
oncogene function and therapeutic responses. Although substantial effort has been made to …
[HTML][HTML] Genome, epigenome and RNA sequences of monozygotic twins discordant for multiple sclerosis
SE Baranzini, J Mudge, JC Van Velkinburgh… - Nature, 2010 - nature.com
Monozygotic or 'identical'twins have been widely studied to dissect the relative contributions
of genetics and environment in human diseases. In multiple sclerosis (MS), an autoimmune …
of genetics and environment in human diseases. In multiple sclerosis (MS), an autoimmune …
Peripheral T cell expansion predicts tumour infiltration and clinical response
Despite the resounding clinical success in cancer treatment of antibodies that block the
interaction of PD1 with its ligand PDL1, the mechanisms involved remain unknown. A major …
interaction of PD1 with its ligand PDL1, the mechanisms involved remain unknown. A major …