[PDF][PDF] Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis

HS Phillips, S Kharbanda, R Chen, WF Forrest… - Cancer cell, 2006 - cell.com
Previously undescribed prognostic subclasses of high-grade astrocytoma are identified and
discovered to resemble stages in neurogenesis. One tumor class displaying neuronal …

GMAP: a genomic mapping and alignment program for mRNA and EST sequences

TD Wu, CK Watanabe - Bioinformatics, 2005 - academic.oup.com
Motivation: We introduce gmap, a standalone program for mapping and aligning cDNA
sequences to a genome. The program maps and aligns a single sequence with minimal …

Fast and SNP-tolerant detection of complex variants and splicing in short reads

TD Wu, S Nacu - Bioinformatics, 2010 - academic.oup.com
Motivation: Next-generation sequencing captures sequence differences in reads relative to a
reference genome or transcriptome, including splicing events and complex variants …

Comprehensive genomic analysis identifies SOX2 as a frequently amplified gene in small-cell lung cancer

CM Rudin, S Durinck, EW Stawiski, JT Poirier… - Nature …, 2012 - nature.com
Small-cell lung cancer (SCLC) is an exceptionally aggressive disease with poor prognosis.
Here, we obtained exome, transcriptome and copy-number alteration data from …

[HTML][HTML] Recurrent R-spondin fusions in colon cancer

S Seshagiri, EW Stawiski, S Durinck, Z Modrusan… - Nature, 2012 - nature.com
Identifying and understanding changes in cancer genomes is essential for the development
of targeted therapeutics. Here we analyse systematically more than 70 pairs of primary …

Comprehensive genomic analysis of malignant pleural mesothelioma identifies recurrent mutations, gene fusions and splicing alterations

R Bueno, EW Stawiski, LD Goldstein, S Durinck… - Nature …, 2016 - nature.com
Abstract We analyzed transcriptomes (n= 211), whole exomes (n= 99) and targeted exomes
(n= 103) from 216 malignant pleural mesothelioma (MPM) tumors. Using RNA-seq data, we …

[PDF][PDF] The Secure Remote Password Protocol.

TD Wu - NDSS, 1998 - Citeseer
This paper presents a new password authentication and key-exchange protocol suitable for
authenticating users and exchanging keys over an untrusted network. The new protocol …

A comprehensive transcriptional portrait of human cancer cell lines

C Klijn, S Durinck, EW Stawiski, PM Haverty… - Nature …, 2015 - nature.com
Tumor-derived cell lines have served as vital models to advance our understanding of
oncogene function and therapeutic responses. Although substantial effort has been made to …

[HTML][HTML] Genome, epigenome and RNA sequences of monozygotic twins discordant for multiple sclerosis

SE Baranzini, J Mudge, JC Van Velkinburgh… - Nature, 2010 - nature.com
Monozygotic or 'identical'twins have been widely studied to dissect the relative contributions
of genetics and environment in human diseases. In multiple sclerosis (MS), an autoimmune …

Peripheral T cell expansion predicts tumour infiltration and clinical response

TD Wu, S Madireddi, PE de Almeida, R Banchereau… - Nature, 2020 - nature.com
Despite the resounding clinical success in cancer treatment of antibodies that block the
interaction of PD1 with its ligand PDL1, the mechanisms involved remain unknown. A major …