Pembrolizumab in combination with gemcitabine and cisplatin compared with gemcitabine and cisplatin alone for patients with advanced biliary tract cancer …
RK Kelley, M Ueno, C Yoo, RS Finn, J Furuse, Z Ren… - The Lancet, 2023 - thelancet.com
Background Biliary tract cancers, which arise from the intrahepatic or extrahepatic bile ducts
and the gallbladder, generally have a poor prognosis and are rising in incidence worldwide …
and the gallbladder, generally have a poor prognosis and are rising in incidence worldwide …
[HTML][HTML] Baseline circulating IL-17 predicts toxicity while TGF-β1 and IL-10 are prognostic of relapse in ipilimumab neoadjuvant therapy of melanoma
AA Tarhini, H Zahoor, Y Lin, U Malhotra… - … for immunotherapy of …, 2015 - Springer
Background We evaluated candidate circulating serum cytokines, chemokines and growth
factors in patients with locally/regionally advanced melanoma receiving neoadjuvant …
factors in patients with locally/regionally advanced melanoma receiving neoadjuvant …
Morbidity and mortality associated with gastrectomy for gastric cancer
WA Papenfuss, M Kukar, J Oxenberg, K Attwood… - Annals of surgical …, 2014 - Springer
Background Surgery alone is often inadequate for advanced-stage gastric cancer. Surgical
complications may delay adjuvant therapy. Understanding these complications is needed for …
complications may delay adjuvant therapy. Understanding these complications is needed for …
Hedgehog: an attribute to tumor regrowth after chemoradiotherapy and a target to improve radiation response
J Sims-Mourtada, JG Izzo, S Apisarnthanarax… - Clinical cancer …, 2006 - AACR
Purpose: Despite aggressive chemotherapy, radiotherapy, surgery, or combination
approaches, the survival rate of patients with esophageal cancer remains poor. Recent …
approaches, the survival rate of patients with esophageal cancer remains poor. Recent …
Rodent intestinal folate transporters (SLC46A1): secondary structure, functional properties, and response to dietary folate restriction
A Qiu, SH Min, M Jansen, U Malhotra… - … of physiology-cell …, 2007 - journals.physiology.org
This laboratory recently identified a human gene that encodes a novel folate transporter
[Homo sapiens proton-coupled folate transporter (Hs PCFT); SLC46A1] required for …
[Homo sapiens proton-coupled folate transporter (Hs PCFT); SLC46A1] required for …
[PDF][PDF] Association of activated transcription factor nuclear factor κB with chemoradiation resistance and poor outcome in esophageal carcinoma
JG Izzo, U Malhotra, TT Wu, J Ensor… - Journal of Clinical …, 2006 - jivaresearch.org
Association of Activated Transcription Factor Nuclear Factor κB With Chemoradiation
Resistance and Poor Outcome in Esophageal C Page 1 Association of Activated …
Resistance and Poor Outcome in Esophageal C Page 1 Association of Activated …
Decision-making strategy for rectal cancer management using radiation therapy for elderly or comorbid patients
SJ Wang, L Hathout, U Malhotra… - International Journal of …, 2018 - Elsevier
Rectal cancer predominantly affects patients older than 70 years, with peak incidence at age
80 to 85 years. However, the standard treatment paradigm for rectal cancer oftentimes …
80 to 85 years. However, the standard treatment paradigm for rectal cancer oftentimes …
[HTML][HTML] Management of locally advanced rectal cancer in the elderly: a critical review and algorithm
L Hathout, N Maloney-Patel, U Malhotra… - Journal of …, 2018 - ncbi.nlm.nih.gov
Colorectal cancer incidence and death rates have been declining over the past 10 years.
However, it remains the second leading cause of death in men ages 60–79 and the third …
However, it remains the second leading cause of death in men ages 60–79 and the third …
Small cell carcinoma of the esophagus: a SEER database analysis
Background Small cell cancer (SCC) of the esophagus is an uncommon malignancy with
perceived poor prognosis, but there are few data to guide therapeutic decisions. We …
perceived poor prognosis, but there are few data to guide therapeutic decisions. We …
A multicenter phase II study of gemcitabine, capecitabine, and bevacizumab for locally advanced or metastatic biliary tract cancer
Objectives: Vascular endothelial growth factor overexpression, seen in 42% to 76% of biliary
tract cancers (BTCs), correlates with poor survival. We explored the safety/efficacy and …
tract cancers (BTCs), correlates with poor survival. We explored the safety/efficacy and …