[HTML][HTML] Targeting the tumour: Cell penetrating peptides for molecular imaging and radiotherapy
V Kersemans, B Cornelissen - Pharmaceuticals, 2010 - mdpi.com
Over the last couple of years, the number of original papers and reviews discussing various
applications of cell penetrating peptides (CPPs) has grown exponentially. This is not …
applications of cell penetrating peptides (CPPs) has grown exponentially. This is not …
Cell penetrating peptides for in vivo molecular imaging applications
V Kersemans, K Kersemans… - Current pharmaceutical …, 2008 - ingentaconnect.com
Cell penetrating peptides (CPPs) are a relatively new class of peptides that have the
promising capability to cross cell membranes. While details remain to be resolved, various …
promising capability to cross cell membranes. While details remain to be resolved, various …
Imaging of translocator protein upregulation is selective for pro‐inflammatory polarized astrocytes and microglia
Translocator protein (TSPO) expression is increased in activated glia, and has been used as
a marker of neuroinflammation in PET imaging. However, the extent to which TSPO …
a marker of neuroinflammation in PET imaging. However, the extent to which TSPO …
18F-Trifluoromethylation of Unmodified Peptides with 5-18F-(Trifluoromethyl)dibenzothiophenium Trifluoromethanesulfonate
The 18F-labeling of 5-(trifluoromethyl)-dibenzothiophenium trifluoromethanesulfonate,
commonly referred to as the Umemoto reagent, has been accomplished applying a halogen …
commonly referred to as the Umemoto reagent, has been accomplished applying a halogen …
PET imaging of PARP expression using 18F-olaparib
Poly (ADP-ribose) polymerase (PARP) inhibitors are increasingly being studied as cancer
drugs, as single agents, or as a part of combination therapies. Imaging of PARP using a …
drugs, as single agents, or as a part of combination therapies. Imaging of PARP using a …
Nanographene oxide-based radioimmunoconstructs for in vivo targeting and SPECT imaging of HER2-positive tumors
B Cornelissen, S Able, V Kersemans, PA Waghorn… - Biomaterials, 2013 - Elsevier
Nanographene oxide (NGO) is a novel nano-wall material that tracks to tumors in vivo, and
which, as a consequence of its large surface area, has the capacity to carry a large payload …
which, as a consequence of its large surface area, has the capacity to carry a large payload …
Imaging DNA Damage In Vivo Using γH2AX-Targeted Immunoconjugates
B Cornelissen, V Kersemans, S Darbar, J Thompson… - Cancer research, 2011 - AACR
DNA damage responses (DDR) occur during oncogenesis and therapeutic responses to
DNA damaging cytotoxic drugs. Thus, a real-time method to image DNA damage in vivo …
DNA damaging cytotoxic drugs. Thus, a real-time method to image DNA damage in vivo …
A comparison of the behavior of 64Cu-acetate and 64Cu-ATSM in vitro and in vivo
R Hueting, V Kersemans, B Cornelissen… - Journal of Nuclear …, 2014 - Soc Nuclear Med
64Cu-diacetyl-bis (N 4-methylthiosemicarbazonate), 64Cu-ATSM, continues to be
investigated clinically as a PET agent both for delineation of tumor hypoxia and as an …
investigated clinically as a PET agent both for delineation of tumor hypoxia and as an …
[HTML][HTML] Ultrasound-mediated cavitation enhances the delivery of an EGFR-targeting liposomal formulation designed for chemo-radionuclide therapy
Nanomedicines allow active targeting of cancer for diagnostic and therapeutic applications
through incorporation of multiple functional components. Frequently, however, clinical …
through incorporation of multiple functional components. Frequently, however, clinical …
Imaging DNA damage repair in vivo after 177Lu-DOTATATE therapy
E O'Neill, V Kersemans, PD Allen… - Journal of Nuclear …, 2020 - Soc Nuclear Med
Molecular radiotherapy using 177Lu-DOTATATE is a most effective treatment for
somatostatin receptor–expressing neuroendocrine tumors. Despite its frequent and …
somatostatin receptor–expressing neuroendocrine tumors. Despite its frequent and …