[HTML][HTML] Hypermethylation of CD19 promoter enables antigen-negative escape to CART-19 in vivo and in vitro

A Ledererova, L Dostalova, V Kozlova… - … for Immunotherapy of …, 2021 - ncbi.nlm.nih.gov
Background Anti-CD19 chimeric antigen receptor T cells (CART-19) frequently induce
remissions in hemato-oncological patients with recurred and/or refractory B-cell tumors …

[HTML][HTML] CD20 is dispensable for B-cell receptor signaling but is required for proper actin polymerization, adhesion and migration of malignant B cells

V Kozlova, A Ledererova, A Ladungova, H Peschelova… - Plos one, 2020 - journals.plos.org
Surface protein CD20 serves as the critical target of immunotherapy in various B-cell
malignancies for decades, however its biological function and regulation remain largely …

[HTML][HTML] Neuroorganoleptics: organoleptic testing based on psychophysiological sensing

J Valente, L Godinho, C Pintado, C Baptista, V Kozlova… - Foods, 2021 - mdpi.com
There is an increasing interest, in consumer behaviour research related to food and
beverage, in taking a step further from the traditional self-report questionnaires and …

[HTML][HTML] Performance of anti-CD19 chimeric antigen receptor T cells in genetically defined classes of chronic lymphocytic leukemia

V Mancikova, H Peschelova, V Kozlova… - … for ImmunoTherapy of …, 2020 - ncbi.nlm.nih.gov
Background While achieving prolonged remissions in other B cell-derived malignancies,
chimeric antigen receptor (CAR) T cells still underperform when injected into patients with …

BrainAnswer platform: Biosignals acquisition for monitoring of physical and cardiac conditions of older people

J Valente, V Kozlova, T Pereira - Promoting Healthy and Active …, 2021 - taylorfrancis.com
Remote monitoring tools are promising methodological options to ensure point-of-care
vigilance and assist on clinical decision making in quite diverse clinical contexts. Such …

[HTML][HTML] Epigenetic drug screen on resistant CLL cells reveals aurora kinase inhibitors as enhancers of CD20 expression and sensitizers to treatment with CD20 …

V Kozlová, A Ledererova, M Doubek, J Mayer… - Blood, 2018 - Elsevier
Background: Chronic lymphocytic leukemia (CLL) still remains an incurable disease. In spite
of tremendous success of some targeted agents, the main mode of therapy in routine …

[HTML][HTML] Cellular mechanisms regulating CD20 as a target of monoclonal antibody therapy in B-lymphoid malignancies

M Smida, V Kozlova, V Vakulova, A Ledererova… - Blood, 2016 - Elsevier
Standard treatment of B-lymphoid malignancies nowadays still relies on the administration
of monoclonal antibodies (mAbs), with CD20 antigen being the prime target. Although …

EVALUATION OF THE QUALITY OF HOTEL SERVICES: THE AMERICAN EXPERIENCE

M Medeiros, K Cabral, VA Kozlova… - ИНТЕГРАЦИЯ …, 2019 - elibrary.ru
The hospitality industry is always focused on customer requests. Understanding the desires
of customers is necessary to control the quality of their service. Achieving quality in the …

[DOC][DOC] The oil and gas sector in Iraq and Syria

K Veronika - 2017 - dspace.spbu.ru
The theme of the master's thesis is" Oil and gas sector of Syria and Iraq". A relevance of the
theme is explained by an unstable situation in a region of the Republic of Iraq and the Syrian …

Model of Analysis of Restaurant Services' Regional Market in Context of Intercultural Communication

VA Kozlova, NV Glebova, NA Berezina… - … " Topical Problems of …, 2019 - atlantis-press.com
The necessity of assessing the competitiveness of the restaurant services regional market in
the context of intercultural interaction is substantiated. It provides a possibility of identifying …