User profiles for "author:William Burlingham"

William J Burlingham

Professor of Surgery, University of Wisconsin, Madison
Verified email at surgery.wisc.edu
Cited by 10513

[HTML][HTML] Interleukin 35: a key mediator of suppression and the propagation of infectious tolerance

BM Olson, J Sullivan, W Burlingham - Frontiers in Immunology, 2013 - frontiersin.org
The importance of regulatory T cells (Tregs) in balancing the effector arm of the immune
system is well documented, playing a central role in preventing autoimmunity, facilitating …

An interaction between kynurenine and the aryl hydrocarbon receptor can generate regulatory T cells

JD Mezrich, JH Fechner, X Zhang… - The Journal of …, 2010 - journals.aai.org
The aryl hydrocarbon receptor (AHR) has been known to cause immunosuppression after
binding dioxin. It has recently been discovered that the receptor may be central to T cell …

[HTML][HTML] Identification of a B cell signature associated with renal transplant tolerance in humans

KA Newell, A Asare, AD Kirk, TD Gisler… - The Journal of …, 2010 - Am Soc Clin Investig
Establishing long-term allograft acceptance without the requirement for continuous
immunosuppression, a condition known as allograft tolerance, is a highly desirable …

Regulatory cell therapy in kidney transplantation (The ONE Study): a harmonised design and analysis of seven non-randomised, single-arm, phase 1/2A trials

B Sawitzki, PN Harden, P Reinke, A Moreau… - The Lancet, 2020 - thelancet.com
Background Use of cell-based medicinal products (CBMPs) represents a state-of-the-art
approach for reducing general immunosuppression in organ transplantation. We tested …

[HTML][HTML] IL-17–dependent cellular immunity to collagen type V predisposes to obliterative bronchiolitis in human lung transplants

WJ Burlingham, RB Love… - The Journal of …, 2007 - Am Soc Clin Investig
Bronchiolitis obliterans syndrome (BOS), a process of fibro-obliterative occlusion of the small
airways in the transplanted lung, is the most common cause of lung transplant failure. We …

[HTML][HTML] The effect of tolerance to noninherited maternal HLA antigens on the survival of renal transplants from sibling donors

WJ Burlingham, AP Grailer, DM Heisey… - … England Journal of …, 1998 - Mass Medical Soc
Background During pregnancy and nursing, a baby's developing immune system is
intimately exposed to the mother's antigens. To determine whether this exposure is of …

A new model of Epstein-Barr virus infection reveals an important role for early lytic viral protein expression in the development of lymphomas

SD Ma, S Hegde, KH Young, R Sullivan… - Journal of …, 2011 - Am Soc Microbiol
Epstein-Barr virus (EBV) infects cells in latent or lytic forms, but the role of lytic infection in
EBV-induced lymphomas is unclear. Here, we have used a new humanized mouse model …

Donor-derived exosomes: the trick behind the semidirect pathway of allorecognition

AE Morelli, W Bracamonte-Baran… - Current opinion in …, 2017 - journals.lww.com
Acquisition by recipient APCs of donor exosomes (and likely other extracellular vesicles)
released by passenger leukocytes or the graft explains the potent T-cell allosensitization …

[HTML][HTML] Extracellular matrix scaffold and hydrogel derived from decellularized and delipidized human pancreas

SD Sackett, DM Tremmel, F Ma, AK Feeney… - Scientific Reports, 2018 - nature.com
Extracellular matrix (ECM) plays an important developmental role by regulating cell
behaviour through structural and biochemical stimulation. Tissue-specific ECM, attained …

Functional characterization of human pluripotent stem cell-derived arterial endothelial cells

J Zhang, LF Chu, Z Hou, MP Schwartz… - Proceedings of the …, 2017 - National Acad Sciences
Here, we report the derivation of arterial endothelial cells from human pluripotent stem cells
that exhibit arterial-specific functions in vitro and in vivo. We combine single-cell RNA …