Cancer cell–autonomous contribution of type I interferon signaling to the efficacy of chemotherapy
A Sistigu, T Yamazaki, E Vacchelli, K Chaba, DP Enot… - Nature medicine, 2014 - nature.com
Some of the anti-neoplastic effects of anthracyclines in mice originate from the induction of
innate and T cell–mediated anticancer immune responses. Here we demonstrate that …
innate and T cell–mediated anticancer immune responses. Here we demonstrate that …
Mammalian small stress proteins protect against oxidative stress through their ability to increase glucose-6-phosphate dehydrogenase activity and by maintaining …
X Préville, F Salvemini, S Giraud, S Chaufour… - Experimental cell …, 1999 - Elsevier
The protective activity of small stress proteins (sHsp) against H2O2-mediated cell death in
the highly sensitive murine L929 fibroblast has been analyzed. We report here that the …
the highly sensitive murine L929 fibroblast has been analyzed. We report here that the …
Mechanisms Involved in Antithymocyte Globulin Immunosuppressive Activity in a Nonhuman Primate Model 1
X Préville, M Flacher, B LeMauff, S Beauchard… - …, 2001 - journals.lww.com
Background. The mechanisms of action of polyclonal antithymocyte globulins (ATGs) are still
poorly understood and the selection of doses used in different clinical applications …
poorly understood and the selection of doses used in different clinical applications …
Immune checkpoint blockade, immunogenic chemotherapy or IFN-α blockade boost the local and abscopal effects of oncolytic virotherapy
L Fend, T Yamazaki, C Remy, C Fahrner, M Gantzer… - Cancer research, 2017 - AACR
Athough the clinical efficacy of oncolytic viruses has been demonstrated for local treatment,
the ability to induce immune-mediated regression of distant metastases is still poorly …
the ability to induce immune-mediated regression of distant metastases is still poorly …
Eradication of Established Tumors by Vaccination With Recombinant Bordetella pertussis Adenylate Cyclase Carrying the Human Papillomavirus 16 E7 Oncoprotein
X Préville, D Ladant, B Timmerman, C Leclerc - Cancer research, 2005 - AACR
High-risk human papillomaviruses (HPV) such as HPV16 are associated with the
development of cervical cancer. The HPV16-E6 and HPV16-E7 oncoproteins are expressed …
development of cervical cancer. The HPV16-E6 and HPV16-E7 oncoproteins are expressed …
Vectorization in an oncolytic vaccinia virus of an antibody, a Fab and a scFv against programmed cell death-1 (PD-1) allows their intratumoral delivery and an …
P Kleinpeter, L Fend, C Thioudellet, M Geist… - …, 2016 - Taylor & Francis
We report here the successful vectorization of a hamster monoclonal IgG (namely J43)
recognizing the murine Programmed cell death-1 (mPD-1) in Western Reserve (WR) …
recognizing the murine Programmed cell death-1 (mPD-1) in Western Reserve (WR) …
Eradication of large tumors in mice by a tritherapy targeting the innate, adaptive, and regulatory components of the immune system
P Berraondo, C Nouzé, X Préville, D Ladant, C Leclerc - Cancer research, 2007 - AACR
Targeting the human papillomavirus (HPV) E7 antigen to dendritic cells with the adenylate
cyclase (CyaA) of Bordetella pertussis as a vaccine vector led to potent therapeutic immune …
cyclase (CyaA) of Bordetella pertussis as a vaccine vector led to potent therapeutic immune …
[HTML][HTML] Therapeutic effects of anti-CD115 monoclonal antibody in mouse cancer models through dual inhibition of tumor-associated macrophages and osteoclasts
L Fend, N Accart, J Kintz, S Cochin, C Reymann… - PLoS …, 2013 - journals.plos.org
Tumor progression is promoted by Tumor-Associated Macrophages (TAMs) and metastasis-
induced bone destruction by osteoclasts. Both myeloid cell types depend on the CD115 …
induced bone destruction by osteoclasts. Both myeloid cell types depend on the CD115 …
[HTML][HTML] Viral based vaccine TG4010 induces broadening of specific immune response and improves outcome in advanced NSCLC
C Tosch, B Bastien, L Barraud, B Grellier… - … for immunotherapy of …, 2017 - Springer
Background Advanced non-small cell lung cancer patients receiving TG4010, a therapeutic
viral vaccine encoding human Mucin 1 and interleukin-2 in addition to standard …
viral vaccine encoding human Mucin 1 and interleukin-2 in addition to standard …
Sequential administration of MVA-based vaccines and PD-1/PD-L1-blocking antibodies confers measurable benefits on tumor growth and survival: Preclinical studies …
C Remy-Ziller, C Thioudellet, J Hortelano… - Human vaccines & …, 2018 - Taylor & Francis
ABSTRACT TG4010, a Modified Vaccinia virus Ankara (MVA) expressing human mucin1
(MUC1) has demonstrated clinical benefit for patients suffering from advanced non-small …
(MUC1) has demonstrated clinical benefit for patients suffering from advanced non-small …