[HTML][HTML] Level of circulating PD-L1 expression in patients with advanced gastric cancer and its clinical implications

Z Zheng, Z Bu, X Liu, L Zhang, Z Li, A Wu… - Chinese Journal of …, 2014 - ncbi.nlm.nih.gov
Objective The programmed cell death-1 receptor/programmed cell death-1 ligand (PD-1/PD-
L1) pathway plays a crucial role in tumor evasion from host immunity. This study was …

Analysis of PD1, PDL1, PDL2 expression and T cells infiltration in 1014 gastric cancer patients

X Xing, J Guo, G Ding, B Li, B Dong, Q Feng, S Li… - …, 2018 - Taylor & Francis
Although immune checkpoint blockade have demonstrated promising results, their effects on
gastric cancer (GC) are under investigation. Understanding the clinical significance of PD1 …

[HTML][HTML] PRL-3 promotes the motility, invasion, and metastasis of LoVo colon cancer cells through PRL-3-integrin β1-ERK1/2 and-MMP2 signaling

L Peng, X Xing, W Li, L Qu, L Meng, S Lian, B Jiang… - Molecular cancer, 2009 - Springer
Background Phosphatase of regenerating liver-3 (PRL-3) plays a causative role in tumor
metastasis, but the underlying mechanisms are not well understood. In our previous study …

[HTML][HTML] Effect of neoadjuvant chemotherapy on the immune microenvironment in gastric cancer as determined by multiplex immunofluorescence and T cell receptor …

X Xing, J Shi, Y Jia, Y Dou, Z Li, B Dong… - … for immunotherapy of …, 2022 - ncbi.nlm.nih.gov
Background The combination of immune checkpoint blockade and chemotherapy has
revolutionized the treatment of advanced gastric cancer (GC). It is crucial to unravel …

[HTML][HTML] TRIM28 promotes the escape of gastric cancer cells from immune surveillance by increasing PD-L1 abundance

X Ma, S Jia, G Wang, M Liang, T Guo, H Du… - … and Targeted Therapy, 2023 - nature.com
Immune checkpoint blockade (ICB) offers a new opportunity for treatment for gastric cancer
(GC). Understanding the upstream regulation of immune checkpoints is crucial to further …

Neoadjuvant PD-1 blockade plus chemotherapy induces a high pathological complete response rate and anti-tumor immune subsets in clinical stage III gastric cancer

X Tang, M Li, X Wu, T Guo, L Zhang, L Tang… - …, 2022 - Taylor & Francis
First-line PD-1 blockade plus chemotherapy significantly improves the survival benefits in
late-stage gastric cancer (GC) patients. However, the pathological response rate and effects …

Multi-omics characterization of molecular features of gastric cancer correlated with response to neoadjuvant chemotherapy

Z Li, X Gao, X Peng, MJ May Chen, Z Li, B Wei… - Science …, 2020 - science.org
Neoadjuvant chemotherapy is a common treatment for patients with gastric cancer. Although
its benefits have been demonstrated, neoadjuvant chemotherapy is underutilized in gastric …

EGR1‐mediated linc01503 promotes cell cycle progression and tumorigenesis in gastric cancer

Z Ma, X Gao, Y Shuai, X Wu, Y Yan, X Xing… - Cell proliferation, 2021 - Wiley Online Library
Abstract Objectives Long non‐coding RNAs (lncRNAs) are key mediators in various
malignancies. Linc01503 was previously elucidated to promote gastric cancer (GC) cell …

Prognostic significance of phosphatase of regenerating liver-3 expression in ovarian cancer

T Ren, B Jiang, X Xing, B Dong, L Peng, L Meng… - Pathology & Oncology …, 2009 - Springer
Phosphatase of regenerating liver-3 (PRL-3) is overexpressed in several human cancers
and associated with tumor progression, invasion and metastasis. However, the correlation …

PINA 3.0: mining cancer interactome

Y Du, M Cai, X Xing, J Ji, E Yang… - Nucleic Acids Research, 2021 - academic.oup.com
Protein–protein interactions (PPIs) are crucial to mediate biological functions, and
understanding PPIs in cancer type-specific context could help decipher the underlying …