Ferroptosis is a novel form of regulated cell death characterized by accumulated lipid
reactive oxygen species (ROS) and inactivation of glutathione peroxidase 4 (GPX4). The …

Pancreatic ductal adenocarcinoma (PDAC) is an extremely aggressive pancreatic cancer
with poor survival rate. Circular RNAs (circRNAs) signatures have been identified in some …

Prostate cancer (PCa) remains a leading cause of mortality among men in the United States
and Western Europe. The molecular mechanism of PCa pathogenesis has not been fully …

Background High-grade gliomas are rapidly progressing tumors of the central nervous
system, and are associated with poor prognosis and highly immunosuppressive …

Pancreatic cancer (PC) remains a major health concern, with conventional cancer
treatments exerting little influence on the disease course. MicroRNA-520b (miR-520b) …

Non-small cell lung cancer (NSCLC) represents 75–80% of all lung carcinomas, which is the
most common cause of death from cancer. Tumour suppressor candidate 3 (TUSC3) is …

RUNX2 is overexpressed in gastric cancer but the mechanism (s) through which it promotes
tumor progression remain undefined. Here, we investigated the role of RUNX2 on gastric …

Early identification of gastric cancer (GC) is associated with a superior survival rate
compared to advanced GC. However, the poor specificity and sensitivity of traditional …

Abstract NAD (P) H: quinone oxidoreductase 1 (NQO1), a phase II flavoenzyme that
catalyzes reduction reactions to protect cells against electrophiles and oxidants, is involved …

In clinical diagnostics, single nucleotide polymorphism (SNP)-based microarray analysis
enables the detection of copy number variations (CNVs), as well as copy number neutral …