User profiles for "author:Xu Cao"

xu cao

- Verified email at jhmi.edu - Cited by 20690

Xu-Liang Cao

- Verified email at hc-sc.gc.ca - Cited by 4280

Xu Cao

- Verified email at impcas.ac.cn - Cited by 908

The meaning, the sense and the significance: translating the science of mesenchymal stem cells into medicine

P Bianco, X Cao, PS Frenette, JJ Mao, PG Robey… - Nature medicine, 2013 - nature.com
Mesenchymal stem cells (MSCs) are the focus of intensive efforts worldwide directed not
only at elucidating their nature and unique properties but also developing cell-based …

[HTML][HTML] Electron-ion collider in China

DP Anderle, V Bertone, X Cao, L Chang, N Chang… - Frontiers of …, 2021 - Springer
Lepton scattering is an established ideal tool for studying inner structure of small particles
such as nucleons as well as nuclei. As a future high energy nuclear physics project, an …

[HTML][HTML] Transforming growth factor-β in stem cells and tissue homeostasis

X Xu, L Zheng, Q Yuan, G Zhen, JL Crane, X Zhou… - Bone research, 2018 - nature.com
Abstract TGF-β 1–3 are unique multi-functional growth factors that are only expressed in
mammals, and mainly secreted and stored as a latent complex in the extracellular matrix …

TGF-β1–induced migration of bone mesenchymal stem cells couples bone resorption with formation

Y Tang, X Wu, W Lei, L Pang, C Wan, Z Shi, L Zhao… - Nature medicine, 2009 - nature.com
Bone remodeling depends on the precise coordination of bone resorption and subsequent
bone formation. Disturbances of this process are associated with skeletal diseases, such as …

Inhibition of TGF-β signaling in mesenchymal stem cells of subchondral bone attenuates osteoarthritis

G Zhen, C Wen, X Jia, Y Li, JL Crane, SC Mears… - Nature medicine, 2013 - nature.com
Osteoarthritis is a highly prevalent and debilitating joint disorder. There is no effective
medical therapy for the condition because of limited understanding of its pathogenesis. We …

PDGF-BB secreted by preosteoclasts induces angiogenesis during coupling with osteogenesis

H Xie, Z Cui, L Wang, Z Xia, Y Hu, L Xian, C Li, L Xie… - Nature medicine, 2014 - nature.com
Osteogenesis during bone modeling and remodeling is coupled with angiogenesis. A recent
study showed that a specific vessel subtype, strongly positive for CD31 and endomucin …

Matrix IGF-1 maintains bone mass by activation of mTOR in mesenchymal stem cells

L Xian, X Wu, L Pang, M Lou, CJ Rosen, T Qiu… - Nature medicine, 2012 - nature.com
Insulin-like growth factor 1 (IGF-1), the most abundant growth factor in the bone matrix,
maintains bone mass in adulthood. We now report that IGF-1 released from the bone matrix …

[PDF][PDF] Human-iPSC-derived cardiac stromal cells enhance maturation in 3D cardiac microtissues and reveal non-cardiomyocyte contributions to heart disease

E Giacomelli, V Meraviglia, G Campostrini, A Cochrane… - Cell stem cell, 2020 - cell.com
Cardiomyocytes (CMs) from human induced pluripotent stem cells (hiPSCs) are functionally
immature, but this is improved by incorporation into engineered tissues or forced contraction …

Dietary exposure of Canadians to perfluorinated carboxylates and perfluorooctane sulfonate via consumption of meat, fish, fast foods, and food items prepared in their …

SA Tittlemier, K Pepper, C Seymour… - Journal of agricultural …, 2007 - ACS Publications
Human exposure to perfluorinated compounds is a worldwide phenomenon; however,
routes of human exposure to these compounds have not been well-characterized. Fifty-four …

Domestication of wild tomato is accelerated by genome editing

T Li, X Yang, Y Yu, X Si, X Zhai, H Zhang, W Dong… - Nature …, 2018 - nature.com
Crop improvement by inbreeding often results in fitness penalties and loss of genetic
diversity. We introduced desirable traits into four stress-tolerant wild-tomato accessions by …