User profiles for "author:Yiyin Chen"

Yiyin Chen

Johns Hopkins University
Verified email at jh.edu
Cited by 1636

Aging in COVID-19: Vulnerability, immunity and intervention

Y Chen, SL Klein, BT Garibaldi, H Li, C Wu… - Ageing research …, 2021 - Elsevier
The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) pandemic was first
reported in Wuhan, China in December 2019, moved across the globe at an unprecedented …

The skin microbiome: current perspectives and future challenges

YE Chen, H Tsao - Journal of the American Academy of Dermatology, 2013 - Elsevier
Complex communities of bacteria, fungi, and viruses thrive on our skin. The composition of
these communities depends on skin characteristics, such as sebaceous gland …

The biology of aging and cancer: frailty, inflammation, and immunity

X Zhang, X Meng, Y Chen, SX Leng… - The Cancer Journal, 2017 - journals.lww.com
The majority of patients with common malignancies are older adults. Intrinsic complex
biological changes of aging along with inflammation, immunosenescence, age-associated …

Comparison of pain perception, anxiety, and impacts on oral health-related quality of life between patients receiving clear aligners and fixed appliances during the …

M Gao, X Yan, R Zhao, Y Shan, Y Chen… - European journal of …, 2021 - academic.oup.com
Abstract Background and Objectives Clear aligner is an advanced orthodontic method with
benefits of comfort, aesthetics, and convenience. This study aimed to compare pain …

Copper-catalyzed P-arylation via direct coupling of diaryliodonium salts with phosphorus nucleophiles at room temperature

J Xu, P Zhang, Y Gao, Y Chen, G Tang… - The Journal of Organic …, 2013 - ACS Publications
A new method for copper-catalyzed P–C bond formation through reaction of phosphorus
nucleophiles with diaryliodonium salts at room temperature is described. Most target …

MIR155HG is a prognostic biomarker and associated with immune infiltration and immune checkpoint molecules expression in multiple cancers

L Peng, Z Chen, Y Chen, X Wang, N Tang - Cancer medicine, 2019 - Wiley Online Library
In recent years, immune checkpoint inhibitor has achieved remarkable success in multiple
cancer treatment. However, how to pre‐judge which patients are suitable for immune …

Baicalin loaded in folate-PEG modified liposomes for enhanced stability and tumor targeting

Y Chen, J Liu, B Angelov, M Drechsler… - Colloids and Surfaces B …, 2016 - Elsevier
Bioavailability of baicalin (BAI), an example of traditional Chinese medicine, has been
modified by loading into liposome. Several liposome systems of different composition ie …

LncRNA MIAT correlates with immune infiltrates and drug reactions in hepatocellular carcinoma

L Peng, Y Chen, Q Ou, X Wang, N Tang - International …, 2020 - Elsevier
Long non-coding RNA (lncRNA) is a kind of important molecules involved in the formation of
immune landscape in tumor microenvironment. However, there are few studies on the …

Chronic low-grade inflammatory phenotype (CLIP) and senescent immune dysregulation

Y Chen, S Liu, SX Leng - Clinical therapeutics, 2019 - Elsevier
Purpose The aim was to provide an overview of chronic low-grade inflammatory phenotype
(CLIP) and evidence for its role in the pathogenesis of frailty and other chronic conditions as …

[HTML][HTML] MITF modulates therapeutic resistance through EGFR signaling

Z Ji, YE Chen, R Kumar, M Taylor, CNJ Njauw… - Journal of Investigative …, 2015 - Elsevier
Response to targeted therapies varies significantly despite shared oncogenic mutations.
Nowhere is this more apparent than in BRAF (V600E)-mutated melanomas where initial …