… Marjolijn N. Lub-de Hooge … Immuno-PET detected all primary tumors (n = 17) as well as
lymph node metastases in 18 of 25 positive neck levels. Missed lymph nodes were relatively …

Bispecific antibodies (bsAbs) are antibodies that bind two distinct epitopes to cancer.. For
use in oncology, one bsAb has been approved and 57 bsAbs are in clinical trials, none of …

More than 50 monoclonal antibodies (mAbs), including several antibody–drug conjugates,
are in advanced clinical development, forming an important part of the many molecularly …

Programmed cell death protein-1/ligand-1 (PD-1/PD-L1) blockade is effective in a subset of
patients with several tumor types, but predicting patient benefit using approved diagnostics is …

Vascular endothelial growth factor (VEGF), released by tumor cells, is an important growth
factor in tumor angiogenesis. The humanized monoclonal antibody bevacizumab blocks VEGF…

Purpose The cardiac and antineoplastic effects of trastuzumab may be related to specific
uptake of trastuzumab in myocardium and tumor tissue, respectively. We evaluated whether …

The anti–human epidermal growth factor receptor 2 (HER2/neu) antibody trastuzumab is
administered to patients with HER2/neu-overexpressing breast cancer. Whole-body …

… d, Violin plot of SUV max in patients with pMMR (n = 25) and dMMR tumors (n = 9). e, Violin
plot of SUV max in lesions with desert (n = 15) and nondesert (n = 19) immune phenotype …

Trastuzumab (Herceptin®) is a recombinant humanised IgG1 monoclonal antibody against
the human epidermal growth factor receptor 2 (HER2), used for metastatic breast cancer …

Purpose: To provide proof of principle of safety, breast tumor–specific uptake, and positive
tumor margin assessment of the systemically administered near-infrared fluorescent tracer …